Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P91580
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P91580-F1 | Predicted | AlphaFoldDB |
No variants for P91580
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P91580 | |||||
No associated diseases with P91580
1 regional properties for P91580
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Small GTP-binding protein domain | 16 - 168 | IPR005225 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| endosome | A vacuole to which materials ingested by endocytosis are delivered. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| Rab protein signal transduction | The series of molecular signals within the cell that are mediated by a member of the Rab family of proteins switching to a GTP-bound active state. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLQSGEGSPT | LPKRVFKIIV | IGDSDVGKTC | LTYRFCTGKF | PEKTEATIGV | DFRERTLDID |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GEQIKLQLWD | TAGQERFRKS | MVPHYYRNVH | AVVFTYDVTK | GRSFQGLPSW | IEECERYSLN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ASEIPRILVG | NKCDLKDQAE | VDTNSATRFA | DANSMPLFET | SAKADSEMGN | IEAIFLTVAH |
| 190 | 200 | 210 | |||
| KLKSQKPMMK | QDYPNMKRAT | VLSVDKEVLR | TNEAPCSC |