P87367

PR
Gene name
Protein name
Red-sensitive opsin
Names
KFH-R, Red cone photoreceptor pigment
Species
Oryzias latipes (Japanese rice fish) (Japanese killifish)
KEGG Pathway
ola:100049258
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-50 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P87367

Entry ID Method Resolution Chain Position Source
AF-P87367-F1 Predicted AlphaFoldDB

No variants for P87367

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P87367

No associated diseases with P87367

2 regional properties for P87367

Type Name Position InterPro Accession
domain GPCR, rhodopsin-like, 7TM 67 - 319 IPR017452
binding_site Visual pigments (opsins) retinal binding site 303 - 319 IPR027430

Functions

Description
EC Number
Subcellular Localization
  • Membrane; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
photoreceptor outer segment The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.

1 GO annotations of molecular function

Name Definition
G protein-coupled photoreceptor activity Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.

4 GO annotations of biological process

Name Definition
cellular response to light stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
G protein-coupled receptor signaling pathway The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane.
phototransduction The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
visual perception The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAEQWGKQVF AARRQNEDTT RGSAFTYTNS NHTRDPFEGP NYHIAPRWVY NLATLWMFFV
70 80 90 100 110 120
VVLSVFTNGL VLVATAKFKK LRHPLNWILS NLAIADLGET VFASTISVCN QFFGYFILGH
130 140 150 160 170 180
PMCVFEGYVV STCGIAALWS LTIISWERWV VVCKPFGNVK FDAKWAIGGI VFSWVWSAVW
190 200 210 220 230 240
CAPPVFGWSR YWPHGLKTSC GPDVFSGSDD PGVQSYMIVL MITCCIIPLA IIILCYLAVW
250 260 270 280 290 300
LAIRAVAMQQ KESESTQKAE REVSRMVVVM IVAYCVCWGP YTFFACFAAA NPGYAFHPLA
310 320 330 340 350
AAMPAYFAKS ATIYNPVIYV FMNRQFRTCI MQLFGKQVDD GSEVSTSKTE VSSVAPA