P87234
Gene name |
gyp3 |
Protein name |
GTPase-activating protein gyp3 |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPCC4G3.09c |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P87234
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P87234-F1 | Predicted | AlphaFoldDB |
No variants for P87234
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P87234 | |||||
No associated diseases with P87234
5 regional properties for P87234
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | DNA gyrase B subunit, C-terminal | 563 - 620 | IPR002288 |
| domain | Histidine kinase/HSP90-like ATPase | 35 - 182 | IPR003594 |
| domain | TOPRIM domain | 419 - 533 | IPR006171 |
| domain | DNA topoisomerase, type IIA, subunit B, domain 2 | 227 - 392 | IPR013506 |
| domain | DNA gyrase subunit B, TOPRIM domain | 419 - 532 | IPR034160 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTPase activator activity | Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| actin cytoskeleton organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. |
| activation of GTPase activity | Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP. |
| exocytosis | A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAGITEHSTI | MNDANFKEEN | AHLSDASIHF | GSSEQDKTPS | DYELDDVLDL | YNDTTEDDAD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DADDVNNYIM | SPSSSLSSES | EHALDALVYP | IYSHHNILEH | ENNSDYASIT | PSNHPAFTSC |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AYLQNPVVDS | NNEYESKFRL | SLEIPPTDFL | STSTELSKRE | SCLSTETSSS | KFSAVTAATI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TNETQSEKRS | SQTDPSLPFK | TNSLNCDVTY | EEGPLTKKLR | GPKKYKPSHS | SWDIYGFKKA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NQFYTVDQYN | TWYGPYSRYL | ERREQRWKLF | LQENGIDYIH | QSPSIFPSRS | AKTQRFIRKG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IPPEYRGNAW | FYYSGGYELL | QRNPKLYETL | WRCACIKKPS | DSDLIERDLY | RTFPDNVHFR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| HKSKHSRNSS | DASEHSSEEP | DVPMISKLRR | VLMTFATYLP | ENGYCQSLNF | LAGFFLLFMS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| EEKAFWMLVI | TCRKYLPKMH | DANLEGANID | QSVLMASVRE | SLPAVWSRIS | LNFDGIPVND |
| 490 | 500 | 510 | 520 | 530 | 540 |
| IVAKLPPITL | VTAAWFMSAF | VGILPTETAL | RVWDCFFYEG | SKVLFMTALC | ILRLGEDDIK |
| 550 | 560 | 570 | 580 | 590 | 600 |
| SKSEQTEVFQ | VIQDLPKSLL | DANAFLSLCF | RRNFRRTPSQ | KDIERRREKV | AKKRNSSASK |
| 610 | 620 | 630 | |||
| LEMSDSSKHH | LSRSSSRFSK | SHIISQLHNH | LKKST |