P87153
Gene name |
spt7 (SPBC25H2.11c) |
Protein name |
Probable T-complex protein 1 subunit eta |
Names |
TCP-1-eta, CCT-eta |
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPBC25H2.12c |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P87153
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P87153-F1 | Predicted | AlphaFoldDB |
No variants for P87153
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P87153 | |||||
No associated diseases with P87153
3 regional properties for P87153
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Chaperonin TCP-1, conserved site | 41 - 53 | IPR002194-1 |
| conserved_site | Chaperonin TCP-1, conserved site | 62 - 78 | IPR002194-2 |
| conserved_site | Chaperonin TCP-1, conserved site | 90 - 98 | IPR002194-3 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| chaperonin-containing T-complex | A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor. |
| cytoskeleton | A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| ATP-dependent protein folding chaperone | Binding to a protein or a protein-containing complex to assist the protein folding process, driven by ATP hydrolysis. |
| unfolded protein binding | Binding to an unfolded protein. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein folding | The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSLGGPQIPV | IVLKEGTDDS | QGRGQLLSNI | NACVAVQDTI | RTTLGPLGAD | KLMVDDRGEV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VISNDGATIM | KLLDIVHPAA | KTLVDIARAQ | DAEVGDGTTS | VVVFAGELLR | EARTFVEDGV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SSHLIIRGYR | KAAQLAVNKI | KEIAIHLDLS | DEGKLRDLLT | KCASTAMNSK | LIRSNSTFFT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KMVVDAVLTL | DQEDLNENMI | GIKKVPGGAM | EDSLLVKGVA | FKKTFSYAGF | EQQPKFFKNP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KILCLDVELE | LKAEKDNAEV | RVDKVQEYQN | IVDAEWRIIF | SKLEAIVATG | AKVVLSKLPI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GDLATQYFAD | RDIFCAGRVA | ADDLNRVVQA | VGGSIQSTCS | NIEEKHLGTC | DTFEERQIGG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DRFNLFEGCP | KAKTCTLILR | GGADQFIAEV | ERSLHDAIMI | VKHALKNNLV | VAGGGACEME |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LSKYLRDYSL | TISGKQQNFI | AAFARSLEVI | PRQLCDNAGF | DSTNILNKLR | MQHAKGEMWA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| GVDMDSEGVA | NNFEKFVWEP | STVKSNAILS | ATEAATLILS | VDETIKNEPS | QQPQAPQGAL |
| 550 | |||||
| PPGAANRIMR | GRGRGMPR |