P87143

PR
Gene name
SPAC57A7.12
Protein name
Uncharacterized RNA-binding protein C57A7.13
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPAC57A7.13
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-99 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P87143

Entry ID Method Resolution Chain Position Source
AF-P87143-F1 Predicted AlphaFoldDB

8 variants for P87143

Variant ID(s) Position Change Description Diseaes Association Provenance
I_1514454_T_C 59 N>D No Jeffares_SNPs
I_1513819_G_A 229 L>F No Jeffares_SNPs
I_1513798_C_T 236 V>I No Jeffares_SNPs
I_1513782_A_G 241 M>T No Jeffares_SNPs
I_1513477_T_A 343 N>Y No Jeffares_SNPs
I_1513435_A_G 357 Y>H No Jeffares_SNPs
I_1513275_A_G 396 L>S No Jeffares_SNPs
I_1512906_G_A 519 A>V No Jeffares_SNPs

No associated diseases with P87143

4 regional properties for P87143

Type Name Position InterPro Accession
domain G-patch domain 488 - 536 IPR000467
domain RNA recognition motif domain 71 - 151 IPR000504-1
domain RNA recognition motif domain 209 - 293 IPR000504-2
domain Zinc finger, RanBP2-type 153 - 184 IPR001876

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
zinc ion binding Binding to a zinc ion (Zn).

4 GO annotations of biological process

Name Definition
mRNA cis splicing, via spliceosome The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript.
mRNA splicing, via spliceosome The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
regulation of heterochromatin assembly Any process that modulates the frequency, rate, extent or location of heterochromatin formation.
regulation of mRNA splicing, via spliceosome Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKDYYSENGF EEIFEEKGST SSNISDNCAS RDYDVNISSD NPRLLDSYRP KGNYGRDRNS
70 80 90 100 110 120
PLSRHIGVPN QEIILQGLTP EILEEHIELA LYATGAKVST VTLIREKETQ KSRCFAFAKF
130 140 150 160 170 180
VSLQDSKDWM EANFPTLVID GIDVSVRFSR AAREQIEGWC CQNCDILNYS YRESCFKCRV
190 200 210 220 230 240
PRNQASIAIG NHKISKRNGD MDVSDVPSVY LILRNLDRSL SEETLWKGLS KLEIDVQRVF
250 260 270 280 290 300
MIRYKFNDAF CGYAILEFKD VDESAKALMK ARTYPGKGFT LASRKVSVDY IHDGVLIPAY
310 320 330 340 350 360
TESARWQFPT KTGYLVYWDP ELYCSIYVPE GIDTDQFKPI EVNKKPKKEK RARSSNYIDV
370 380 390 400 410 420
PASKKVATSL QRWNDAQKEL KDNIPDLSEE EEKLLLHFVW KSALICVLCE RKFQSWGHVV
430 440 450 460 470 480
KHITQSIMHN NNLKNHELVS SAELLMHRVR QTESVDYRDR ATERRIVPAA SSDTIVEAKK
490 500 510 520 530 540
SSQGSSFHST SNVSMKMLNS MGWNKGSGLG TNENGIKEAI QPTMYLPGVG LGNKGSKIQI
550 560
NMTPVDRVKD RARSLYFQND KNNNL