P87056
Gene name |
SPAC57A10.07 |
Protein name |
Abhydrolase domain-containing protein C57A10.08c |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPAC57A10.08c |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P87056
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P87056-F1 | Predicted | AlphaFoldDB |
10 variants for P87056
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| I_1379659_A_G | 30 | Y>H | No | Jeffares_SNPs | |
| I_1379629_G_T | 40 | R>S | No | Jeffares_SNPs | |
| I_1379553_G_A | 65 | S>F | No | Jeffares_SNPs | |
| I_1379482_T_A | 89 | I>F | No | Jeffares_SNPs | |
| I_1379479_T_C | 90 | I>V | No | Jeffares_SNPs | |
| I_1379476_G_A | 91 | P>S | No | Jeffares_SNPs | |
| I_1379264_T_A | 161 | K>N | No | Jeffares_SNPs | |
| I_1379248_G_C | 167 | L>V | No | Jeffares_SNPs | |
| I_1378873_G_A | 292 | P>S | No | Jeffares_SNPs | |
| I_1378583_G_A | 358 | S>L | No | Jeffares_SNPs |
No associated diseases with P87056
1 regional properties for P87056
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Serine aminopeptidase, S33 | 99 - 321 | IPR022742 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| lipid droplet | An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| hydrolase activity, acting on ester bonds | Catalysis of the hydrolysis of any ester bond. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular lipid metabolic process | The chemical reactions and pathways involving lipids, as carried out by individual cells. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MYFFTISRLT | SFISYGILGA | LGILTFLYLY | DAYLAKSFQR | LVIERRSKRE | SLSKNLSPND |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NSHNSKIDIS | SDYQLLNEYK | VAYYLRPGII | PLNHNLAKQE | VFVFLHGLGG | QMSQFQKVMS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YFPPTACLFS | FDYWGCGLSR | QAFPNQRIGS | VDQLTTKGLS | KLTYKVLEKL | FPENTQFILI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GHSMGATIAS | RVSKMLQTRC | TALLLLNPKI | RFTSKEISMI | VRLRKTPNAF | ISLYRLLDRF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| HGLRSSSVTR | SLSKNIKGDG | DAVRAQLWLW | NRQSNTKIWK | TMLMGLEELL | EPGFHFPKCP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ILILFGEFDP | VSSLKDKVFF | QDYPGNYTFK | EIDTGHCSML | EQPSEVYNCI | DSFLDKFSTT |
| DHNI |