P86325

PR
Gene name
Protein name
Carboxylesterase
Names
Species
Thermobifida fusca (Thermomonospora fusca)
KEGG Pathway
EC number
3.1.1.1: Carboxylic ester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

9-86 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

5 structures for P86325

Entry ID Method Resolution Chain Position Source
7W1I X-ray 167 A A 1-497 PDB
7W1J X-ray 192 A A 1-497 PDB
7W1K X-ray 139 A A 1-497 PDB
7W1L X-ray 244 A A 1-497 PDB
AF-P86325-F1 Predicted AlphaFoldDB

No variants for P86325

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P86325

No associated diseases with P86325

2 regional properties for P86325

Type Name Position InterPro Accession
domain Carboxylesterase, type B 4 - 478 IPR002018
active_site Carboxylesterase type B, active site 172 - 187 IPR019826

Functions

Description
EC Number 3.1.1.1 Carboxylic ester hydrolases
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

2 GO annotations of molecular function

Name Definition
carboxylic ester hydrolase activity Catalysis of the hydrolysis of a carboxylic ester bond.
methyl indole-3-acetate esterase activity Catalysis of the reaction: methyl indole-3-acetate + H2O = indole-3-acetate + methanol + H+.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEIVIRTGSG DVRGSKENGI AVFRGIPYAE PPVGAHRFTA PRPPRPWDGV RDATEFSATA
70 80 90 100 110 120
PRPPYPEAIG ALLIERFIPG DDYLTLNVWT PDPNAVGLPV MVWIHGGAFT NGSGSEPVYD
130 140 150 160 170 180
GAAFARDGVV FVSFNYRLGI IGFADLPDAP SNRGLLDQIA ALEWVRDNIA RFGGDPGNVT
190 200 210 220 230 240
VFGESAGAMS VCTLMATPRA RGLFRRAILQ SGAGNMAVAA EDATTIAAVI AHRLGVEPTA
250 260 270 280 290 300
AALAHVPVAQ LLDVQQQVAQ EIQGAPDPAV WGERIAGGSV LLPFAPVIDG ELLSQRPAEA
310 320 330 340 350 360
IAGGAGHDVD LLFGTTTDEY RLFLAPTGLL PFITSDYVTA HLAKSGLDAD AAKAYTAEGR
370 380 390 400 410 420
GEEPGDILAS IITDQVFRIP ALRIAESRVD APARTFGYEF AWRTPQLDGI LGACHAVELP
430 440 450 460 470 480
FVFRTLDRAA SLVGTNPPEE LAETVHNAWV RFATSGDPGW PAWNPETRSV MRFDHPVSEM
490
VTDPYPATRA LWDGVPL