Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P84285
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P84285-F1 | Predicted | AlphaFoldDB |
No variants for P84285
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P84285 | |||||
No associated diseases with P84285
No regional properties for P84285
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P84285 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| sterol O-acyltransferase activity | Catalysis of the reaction: acyl-CoA + a sterol = CoA + a sterol ester. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| cholesterol metabolic process | The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGRTNTSDQL | NAISDKNTKR | KSLALDNEYH | NNSSSEDDSS | KIELSYTIPD | NNNIISQETT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TSVEDVLSLS | SAPQNELRLR | KQKSNNQDSP | VDLNGVIVDV | SKREKIFLKR | KRQIDNKHGS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DKSKYLSRFN | DITFKAKSST | IFESDEFYKT | DFFGMYVLFW | LATAFAMVNN | LIHTYFENST |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PILQWTVVKV | FKRDLFKVGL | VDLAMYLSTY | FAFFVQYACK | NGYLSWKKVG | WWLQAAFDGL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FLFFWLWIAS | EYCLDFPWIA | KVFLVLHSLV | FIMKMHSYAF | YNGYLWSIYK | EGLYSEKYLD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KLTNGKVTLP | KGHTKNETEK | VLQESIAFTK | YELEYQSHAT | TENPDDHHVF | DIDQTDKSIA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KLQQEGLIKF | PQNITLFNYF | EYSMFPTLVY | TLNFPRTKRI | RWSYVFGKTF | GIFGLIFLMI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LIAENNLYPI | VLRCEIARKL | PVSERIPQYF | FLLMDMIPPF | LMVYLFTFFL | IWDAILNAIA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ELSKFADRDF | YGPWWSCTDF | SEFANQWNRC | VHKFLLRHVY | HSSISAFDVN | KQSAAIITFL |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LSSLVHELVM | YVIFGTLRGY | LLLFQMSQIP | LIIMSRSKFM | KDKKVLGNII | CWFGFISGPS |
| IICTLYLVF |