Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P84032
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P84032-F1 | Predicted | AlphaFoldDB |
3 variants for P84032
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| 31 | S>G | No | |||
| 119 | H>Y | No | |||
| 126 | K>N | No |
No associated diseases with P84032
2 regional properties for P84032
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Thyroglobulin type-1 | 4 - 69 | IPR000716-1 |
| domain | Thyroglobulin type-1 | 70 - 127 | IPR000716-2 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular region | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| cysteine-type endopeptidase inhibitor activity | Binds to and stops, prevents or reduces the activity of a cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| ARPKSDCEKH | RESTEKTGTI | MKLIPKCKEN | SDYEELQCYE | DSKFCVCYDK | KGHAASPIST |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KVKECGCYLK | QKERKDSGRE | SAIIPQCEED | GKWAKKQLWE | FNKSCWCVDE | KGEQVGKIHH |
| DCDSLKCE |