P83773

PR
Gene name
ACH1
Protein name
Acetyl-CoA hydrolase
Names
Acetyl-CoA deacylase, Acetyl-CoA acylase
Species
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
KEGG Pathway
cal:CAALFM_C502000CA
EC number
3.1.2.1: Thiolester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

203-273 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P83773

Entry ID Method Resolution Chain Position Source
AF-P83773-F1 Predicted AlphaFoldDB

No variants for P83773

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P83773

No associated diseases with P83773

2 regional properties for P83773

Type Name Position InterPro Accession
domain Acetyl-CoA hydrolase/transferase, N-terminal 10 - 228 IPR003702
domain Acetyl-CoA hydrolase/transferase C-terminal domain 329 - 479 IPR026888

Functions

Description
EC Number 3.1.2.1 Thiolester hydrolases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

2 GO annotations of molecular function

Name Definition
acetate CoA-transferase activity Catalysis of the reaction: acyl-CoA + acetate = a fatty acid anion + acetyl-CoA.
acetyl-CoA hydrolase activity Catalysis of the reaction: acetyl-CoA + H(2)O = acetate + CoA + H(+).

2 GO annotations of biological process

Name Definition
acetate metabolic process The chemical reactions and pathways involving acetate, the anion of acetic acid.
propionate metabolic process, methylcitrate cycle The chemical reactions and pathways involving propionate that occur in the methylcitrate cycle.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSAILKQRVR YAPYLKKLRT GEQCIDLFKH GQYLGWSGFT GVGAPKVIPT TLVDHVEKNN
70 80 90 100 110 120
LQGKLGFHLF VGASAGPEES RWAENNMILT RAPHQVGKPI AAAINDGRTQ FFDKHLSMFP
130 140 150 160 170 180
QDLTYGFYTK DKPNGSNLDY TIIEATAITE DGSIVPGPAV GASPEMISVS DKIIIEVNTK
190 200 210 220 230 240
TPSFEGIHDI DMPVNPPFRQ PYPHTSADFK IGKTAIPVDP EKVVAIVEST SGDKVPPNTP
250 260 270 280 290 300
SDEQSRGIAN HLIEFLEHEV KQGRLPANLH PLQSGIGNIA NAVVEGLASS NFKNLTVWTE
310 320 330 340 350 360
VLQDSFLDFF ESGSLDYATA TSIRLTNDGF KKFYDNWDTY SKKLCLRSQV VSNSPEIIRR
370 380 390 400 410 420
LGVIAMNTPV EVDIYGHANS TNVMGSRMLN GLGGSADFLR NAKLSIMHTP SARPSKVDPT
430 440 450 460 470 480
GLSCIVPMAS HVDQTEHDLD VVVTEQGLAD LRGLAPKARA KVIIDKCSHP DYKPQLQEYY
490 500 510 520
DRSVFYATKK KTLHEPHILR DVFKMHLNFQ ENGTMKLDSW DQKF