P83512

PR
Gene name
Protein name
Snake venom metalloproteinase BaP1
Names
SVMP, Hemorrhagic metalloproteinase BaP1, Bap-1
Species
Bothrops asper (Terciopelo)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

126-223 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

6 structures for P83512

Entry ID Method Resolution Chain Position Source
1ND1 X-ray 193 A A 194-394 PDB
2W12 X-ray 146 A A 194-394 PDB
2W13 X-ray 114 A A 194-394 PDB
2W14 X-ray 108 A A 194-394 PDB
2W15 X-ray 105 A A 194-394 PDB
AF-P83512-F1 Predicted AlphaFoldDB

No variants for P83512

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P83512

No associated diseases with P83512

1 regional properties for P83512

Type Name Position InterPro Accession
domain Transposase IS4-like domain 119 - 385 IPR002559

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

3 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
metalloendopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
toxin activity Interacting selectively with one or more biological molecules in another (target) organism, initiating pathogenesis (leading to an abnormal, generally detrimental state) in the target organism. The activity should refer to an evolved function of the active gene product, i.e. one that was selected for. Examples include the activity of botulinum toxin, and snake venom.

2 GO annotations of biological process

Name Definition
chemotaxis The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIEVLLVTIC LAVFPYQGSS IILESGNVND YEVVYPRKVT ELPKGAVQPK YEDAMQYEFK
70 80 90 100 110 120
VNGEPVVLHL EKNKGLFSED YSETHYSPDG RKIITYPSFE DHCYYHGRIE NDADSTASIS
130 140 150 160 170 180
ACNGLKGHFK LQGETYLIEP LKLSDSEAHA VYKYENVEKE DEAPKMCGVT ETNWESYEPI
190 200 210 220 230 240
KKASQSNLTP EQQRFSPRYI ELAVVADHGI FTKYNSNLNT IRTRVHEMLN TVNGFYRSVD
250 260 270 280 290 300
VHAPLANLEV WSKQDLIKVQ KDSSKTLKSF GEWRERDLLP RISHDHAQLL TAVVFDGNTI
310 320 330 340 350 360
GRAYTGGMCD PRHSVGVVRD HSKNNLWVAV TMAHELGHNL GIHHDTGSCS CGAKSCIMAS
370 380 390 400
VLSKVLSYEF SDCSQNQYET YLTNHNPQCI LNKPLLTVSG NELLEAGE