Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P83493

Entry ID Method Resolution Chain Position Source
AF-P83493-F1 Predicted AlphaFoldDB

No variants for P83493

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P83493

No associated diseases with P83493

3 regional properties for P83493

Type Name Position InterPro Accession
active_site Aspartic peptidase, active site 86 - 97 IPR001969
domain Aspartic peptidase, N-terminal 18 - 44 IPR012848
domain Peptidase family A1 domain 71 - 378 IPR033121

Functions

Description
EC Number
Subcellular Localization
  • Secreted, extracellular space
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

1 GO annotations of molecular function

Name Definition
aspartic-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKWLVLLGLV SISECIVKIP LRRVKTMRKT LSEKNMLNNF LKEHAYRLSQ ISFRGSNLTI
70 80 90 100 110 120
HPLRNTKDLV YLGNITIGTP PQEFQVVSDT GSSDLWVPSD FCAIEACSLH TRFRHLQSST
130 140 150 160 170 180
FRPTNRTFSI TYGCGTVKGV VVHDTVRIGD LVSTDQPFGL STAEHVSRCT PFDGVLGLNY
190 200 210 220 230 240
PSISFWSTIP IFDKLKNEGA ISEPVFAFYL SKDGQEGSVV MFGGVDHRYY KGELNWVPLI
250 260 270 280 290 300
PAGNWMVHMD RIYIERNVIA CSAGCKAVVD TGAAFIEGPK SQVDNMQKFI GARPRGSKYY
310 320 330 340 350 360
VPCSVVNTLP SIIFRINSIN YPVPGRAYIL KNHRGRCYTT FKENQWSPST EIWILGDVFL
370
RLYFSVFDRG HDRIGLARAV