P82805
Gene name |
TOM20-4 |
Protein name |
Mitochondrial import receptor subunit TOM20-4 |
Names |
Translocase of outer membrane 20 kDa subunit 4 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G40930 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P82805
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P82805-F1 | Predicted | AlphaFoldDB |
18 variants for P82805
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH07285740 | 7 | N>I | No | 1000Genomes | |
| tmp_5_16404560_T_A | 13 | F>Y | No | 1000Genomes | |
| ENSVATH07285741 | 15 | H>N | No | 1000Genomes | |
| tmp_5_16404602_A_C | 27 | N>T | No | 1000Genomes | |
| ENSVATH07285746 | 44 | L>I | No | 1000Genomes | |
| ENSVATH03306813 | 90 | S>T | No | 1000Genomes | |
| ENSVATH03306814 | 91 | S>P | No | 1000Genomes | |
| ENSVATH03306815 | 97 | S>N | No | 1000Genomes | |
| ENSVATH00692327 | 97 | S>R | No | 1000Genomes | |
| tmp_5_16405087_A_G | 98 | D>G | No | 1000Genomes | |
| tmp_5_16405624_A_G | 144 | N>S | No | 1000Genomes | |
| ENSVATH07285767 | 149 | M>I | No | 1000Genomes | |
| tmp_5_16405721_A_T | 154 | T>S | No | 1000Genomes | |
| ENSVATH07285768 | 155 | S>N | No | 1000Genomes | |
| ENSVATH07285769 | 181 | Q>* | No | 1000Genomes | |
| ENSVATH07285770 | 181 | Q>L | No | 1000Genomes | |
| tmp_5_16405814_T_C | 185 | S>P | No | 1000Genomes | |
| tmp_5_16405820_C_T | 187 | Q>* | No | 1000Genomes |
No associated diseases with P82805
No regional properties for P82805
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P82805 | |||
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrial outer membrane translocase complex | A large complex of the mitochondrial outer membrane that mediates transport of proteins into all mitochondrial compartments. |
| plant-type vacuole | A closed structure that is completely surrounded by a unit membrane, contains liquid, and retains the same shape regardless of cell cycle phase. An example of this structure is found in Arabidopsis thaliana. |
| plastid | Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. |
| TIM23 mitochondrial import inner membrane translocase complex | The protein transport machinery of the mitochondrial inner membrane that typically transports proteins that possess a matrix-targeting N-terminal presequence. The TIM23 complex contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein-transporting ATPase activity | Primary active carrier-mediated transport of a protein across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| protein insertion into mitochondrial outer membrane | The process comprising the insertion of proteins from outside the organelle into the mitochondrial outer membrane, mediated by large outer membrane translocase complexes. |
| protein targeting to mitochondrion | The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDMQNENERL | MVFEHARKVA | EATYVKNPLD | AENLTRWAGA | LLELSQFQTE | PKQMILEAIL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KLGEALVIDP | KKHDALWLIG | NAHLSFGFLS | SDQTEASDNF | EKASQFFQLA | VEEQPESELY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RKSLTLASKA | PELHTGGTAG | PSSNSAKTMK | QKKTSEFKYD | VFGWVILASY | VVAWISFANS |
| QTPVSRQ |