P82669
Gene name |
MRPS25 (RPMS25) |
Protein name |
28S ribosomal protein S25, mitochondrial |
Names |
MRP-S25, S25mt |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:533011 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
4 structures for P82669
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 3JD5 | EM | 700 A | c | 1-173 | PDB |
| 6NEQ | EM | 332 A | c | 1-173 | PDB |
| 6NF8 | EM | 348 A | c | 1-173 | PDB |
| AF-P82669-F1 | Predicted | AlphaFoldDB |
82 variants for P82669
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs1116991119 | 11 | R>H | No | EVA | |
| rs455252756 | 20 | D>H | No | EVA | |
| rs472052668 | 22 | V>L | No | EVA | |
| rs441460042 | 39 | E>K | No | EVA | |
| rs472229632 | 46 | K>I | No | EVA | |
| rs435986766 | 46 | K>N | No | EVA | |
| rs455997155 | 63 | Q>* | No | EVA | |
| rs444660755 | 69 | N>K | No | EVA | |
| rs474507903 | 69 | N>Y | No | EVA | |
| rs463012240 | 71 | T>K | No | EVA | |
| rs471765106 | 73 | T>S | No | EVA | |
| rs438898694 | 76 | L>Q | No | EVA | |
| rs451518368 | 92 | T>I | No | EVA | |
| rs451333930 | 102 | V>G | No | EVA | |
| rs473140230 | 103 | K>E | No | EVA | |
| rs433621784 | 109 | N>K | No | EVA | |
| rs434199312 | 111 | E>A | No | EVA | |
| rs434199312 | 111 | E>G | No | EVA | |
| rs474171710 | 113 | L>P | No | EVA | |
| rs443395206 | 119 | E>G | No | EVA | |
| rs471854198 | 120 | R>G | No | EVA | |
| rs137204530 | 121 | E>A | No | EVA | |
| rs137204530 | 121 | E>G | No | EVA | |
| rs136426661 | 122 | Q>E | No | EVA | |
| rs461181592 | 123 | L>H | No | EVA | |
| rs449815315 | 125 | H>N | No | EVA | |
| rs458566829 | 125 | H>P | No | EVA | |
| rs477096940 | 125 | H>Q | No | EVA | |
| rs434264431 | 127 | A>G | No | EVA | |
| rs465566931 | 127 | A>P | No | EVA | |
| rs467834167 | 128 | H>D | No | EVA | |
| rs438181765 | 128 | H>P | No | EVA | |
| rs456678709 | 129 | F>I | No | EVA | |
| rs456678709 | 129 | F>L | No | EVA | |
| rs456678709 | 129 | F>V | No | EVA | |
| rs432430633 | 130 | G>E | No | EVA | |
| rs471881310 | 130 | G>R | No | EVA | |
| rs454140341 | 131 | P>A | No | EVA | |
| rs472573706 | 131 | P>H | No | EVA | |
| rs454140341 | 131 | P>T | No | EVA | |
| rs442774939 | 132 | R>P | No | EVA | |
| rs476446455 | 133 | K>E | No | EVA | |
| rs443404970 | 133 | K>N | No | EVA | |
| rs476446455 | 133 | K>Q | No | EVA | |
| rs447300912 | 134 | Y>* | No | EVA | |
| rs458700849 | 134 | Y>D | No | EVA | |
| rs477163119 | 134 | Y>F | No | EVA | |
| rs458700849 | 134 | Y>H | No | EVA | |
| rs458700849 | 134 | Y>N | No | EVA | |
| rs480798427 | 135 | C>F | No | EVA | |
| rs459216898 | 135 | C>R | No | EVA | |
| rs459216898 | 135 | C>S | No | EVA | |
| rs449537432 | 135 | C>W | No | EVA | |
| rs480798427 | 135 | C>Y | No | EVA | |
| rs467918039 | 136 | L>M | No | EVA | |
| rs438240334 | 136 | L>P | No | EVA | |
| rs465541172 | 137 | R>G | No | EVA | |
| rs436369598 | 138 | E>D | No | EVA | |
| rs472635260 | 138 | E>G | No | EVA | |
| rs454203702 | 138 | E>K | No | EVA | |
| rs454880878 | 139 | C>G | No | EVA | |
| rs454880878 | 139 | C>R | No | EVA | |
| rs454880878 | 139 | C>S | No | EVA | |
| rs443482854 | 141 | C>F | No | EVA | |
| rs476517005 | 141 | C>R | No | EVA | |
| rs458693346 | 141 | C>W | No | EVA | |
| rs440920583 | 142 | E>D | No | EVA | |
| rs470792323 | 142 | E>G | No | EVA | |
| rs459279050 | 143 | V>E | No | EVA | |
| rs459279050 | 143 | V>G | No | EVA | |
| rs441572251 | 147 | V>A | No | EVA | |
| rs441572251 | 147 | V>G | No | EVA | |
| rs463157764 | 148 | P>A | No | EVA | |
| rs483343502 | 148 | P>L | No | EVA | |
| rs483343502 | 148 | P>R | No | EVA | |
| rs450347413 | 152 | V>G | No | EVA | |
| rs447830194 | 161 | G>C | No | EVA | |
| rs466277663 | 162 | K>T | No | EVA | |
| rs436430541 | 163 | F>V | No | EVA | |
| rs454942285 | 169 | A>V | No | EVA | |
| rs470161179 | 170 | G>A | No | EVA | |
| rs437113642 | 172 | Q>R | No | EVA |
No associated diseases with P82669
1 regional properties for P82669
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Ribosomal protein/NADH dehydrogenase domain | 36 - 109 | IPR007741 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrial inner membrane | The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. |
| mitochondrial small ribosomal subunit | The smaller of the two subunits of a mitochondrial ribosome. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| mitochondrial translation | The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPMKGRFPIR | RTLQYLSQGD | VVFKDSVKVM | TVNYNTHGEL | GEGARKFVFF | NIPQIQYKNP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| WVQIMLFKNM | TPTPFLRFYL | DSGEQVLVDV | ETKSNKEIME | HVKKILGKNE | ETLRRERQER |
| 130 | 140 | 150 | 160 | 170 | |
| EQLSHPAHFG | PRKYCLRECI | CEVEGQVPCP | AVVPLPRELT | GKFQAALRAG | AQD |