P80868

PR
Gene name
fusA
Protein name
Elongation factor G
Names
EF-G, Vegetative protein 19, VEG19
Species
Bacillus subtilis (strain 168)
KEGG Pathway
bsu:BSU01120
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

166-236 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for P80868

Entry ID Method Resolution Chain Position Source
5VH6 X-ray 261 A A 1-406 PDB
AF-P80868-F1 Predicted AlphaFoldDB

No variants for P80868

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P80868

No associated diseases with P80868

9 regional properties for P80868

Type Name Position InterPro Accession
domain Elongation factor EFG, domain V-like 598 - 685 IPR000640
domain Translational (tr)-type GTP-binding domain 8 - 282 IPR000795
domain Translation elongation factor EFTu-like, domain 2 322 - 389 IPR004161
domain Small GTP-binding protein domain 9 - 181 IPR005225
domain Translation elongation factor EFG/EF2, domain IV 477 - 596 IPR005517
domain Elongation factor G, domain III 403 - 478 IPR009022
conserved_site Tr-type G domain, conserved site 51 - 66 IPR031157
domain EFG, domain V 601 - 678 IPR035649
domain Elongation Factor G, domain II 402 - 475 IPR041095

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation elongation factor activity Functions in chain elongation during polypeptide synthesis at the ribosome.

1 GO annotations of biological process

Name Definition
ribosome disassembly The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAREFSLEKT RNIGIMAHID AGKTTTTERI LFYTGRIHKI GETHEGASQM DWMEQEQERG
70 80 90 100 110 120
ITITSAATTA QWKGYRVNII DTPGHVDFTV EVERSLRVLD GAVAVLDAQS GVEPQTETVW
130 140 150 160 170 180
RQATTYGVPR IVFVNKMDKI GADFLYSVGT LRDRLQANAH AIQLPIGAED NFEGIIDLVE
190 200 210 220 230 240
NVAYFYEDDL GTRSDAKEIP EEYKEQAEEL RNSLIEAVCE LDEELMDKYL EGEEITIDEL
250 260 270 280 290 300
KAGIRKGTLN VEFYPVLVGS AFKNKGVQLV LDAVLDYLPA PTDVAAIKGT RPDTNEEIER
310 320 330 340 350 360
HSSDEEPFSA LAFKVMTDPY VGKLTFFRVY SGTLDSGSYV KNSTKGKRER VGRILQMHAN
370 380 390 400 410 420
SREEISTVYA GDIAAAVGLK DTTTGDTLCD EKDLVILESM EFPEPVIDVA IEPKSKADQD
430 440 450 460 470 480
KMGIALAKLA EEDPTFRTQT NPETGQTIIS GMGELHLDII VDRMKREFKV EANVGAPQVA
490 500 510 520 530 540
YRETFRTGAK VEGKFVRQSG GRGQFGHVWI EFEPNEEGAG FEFENAIVGG VVPREYIPAV
550 560 570 580 590 600
QAGLEDALEN GVLAGFPLID IKAKLFDGSY HDVDSNEMAF KVAASMALKN AVSKCNPVLL
610 620 630 640 650 660
EPIMKVEVVI PEEYMGDIMG DITSRRGRVE GMEARGNAQV VRAMVPLAEM FGYATALRSN
670 680 690
TQGRGTFTMH MDHYEEVPKS VAEEIIKKNK GE