P80650
Gene name |
mtrH |
Protein name |
Tetrahydromethanopterin S-methyltransferase subunit H |
Names |
N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit H |
Species |
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia) |
KEGG Pathway |
mma:MM_1540 |
EC number |
2.1.1.86: Methyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P80650
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P80650-F1 | Predicted | AlphaFoldDB |
No variants for P80650
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P80650 | |||||
No associated diseases with P80650
No regional properties for P80650
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P80650 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.1.1.86 | Methyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| tetrahydromethanopterin S-methyltransferase activity | Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme M = 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M. 2-(methylthio)ethanesulfonate is also known as methyl-CoM. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| methanogenesis, from carbon dioxide | The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other compounds, including carbon dioxide (CO2). |
| methylation | The process in which a methyl group is covalently attached to a molecule. |
| one-carbon metabolic process | The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFKFDKKQEV | FELGGVKFGG | QPGENPTVLV | STMFYARHKI | VTDEDKGIFD | RAAAETLWNT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QVSLSDATGL | PYVNQIVGET | PESIKRYIEW | FVGIDDRTPF | LIDSSAGNVR | AAAAQYCTEI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GVADRAIHNS | INASIEQSEI | DVLTESDVSA | AIVLAFNATD | PTVKGKIDIL | EVGGSGQTKG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| MLQVAKECGI | KYPIIDVAAM | PLGAGSGATI | RSVPTLKGKF | GLPIGGGYHN | MASAWDWLRK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FKKTQPDPKA | IYMPTDIGTN | LVAQIAGSDY | LLYGPIENVN | QIFPAVAMVD | IMLGETAKEL |
| 310 | |||||
| GVEIADLENH | PVTKLT |