P80186
Gene name |
mtrE |
Protein name |
Tetrahydromethanopterin S-methyltransferase subunit E |
Names |
N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit E |
Species |
Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) |
KEGG Pathway |
mmg:MTBMA_c15470 |
EC number |
2.1.1.86: Methyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P80186
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P80186-F1 | Predicted | AlphaFoldDB |
No variants for P80186
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P80186 | |||||
No associated diseases with P80186
No regional properties for P80186
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P80186 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.1.1.86 | Methyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| methyltransferase complex | A protein complex that possesses methyltransferase activity. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| vesicle membrane | The lipid bilayer surrounding any membrane-bounded vesicle in the cell. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| tetrahydromethanopterin S-methyltransferase activity | Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme M = 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M. 2-(methylthio)ethanesulfonate is also known as methyl-CoM. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| methanogenesis, from carbon dioxide | The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other compounds, including carbon dioxide (CO2). |
| methylation | The process in which a methyl group is covalently attached to a molecule. |
| one-carbon metabolic process | The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states. |
| sodium ion transport | The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDPMITGLGV | VALMGAAATI | AGAAEDLESD | VGSQSNPNSQ | VQLAPQMGHL | HRIINKAVSG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EPVAYGTWCG | IAGSVAFVLM | NSMQLPVIMA | IAIGAVIAAM | VHTTYAVTSH | MGRIVSQSQF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NQPLFMDMLV | QHLGPIAGHG | FIVTFCTVGL | SYLMTLPIPG | FAHPFPLPLL | AVLWGITIGA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IGSSTGDVHY | GAEREYQQYP | FGGGIPVAIH | GDITTKAELG | ARNSMDVVHF | CAKYGGPLTG |
| 250 | 260 | 270 | 280 | 290 | |
| FAFGAIVFLS | FWNTIVFGIT | GGIISGLIIV | LLLIILNNRL | EVFARNRYGP | YKEEE |