Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P79801
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P79801-F1 | Predicted | AlphaFoldDB |
No variants for P79801
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P79801 | |||||
No associated diseases with P79801
No regional properties for P79801
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P79801 | |||
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cell periphery | The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures. |
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| aspartic endopeptidase activity, intramembrane cleaving | Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain, occurring within a membrane. |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| amyloid precursor protein catabolic process | The chemical reactions and pathways resulting in the breakdown of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease. |
| intracellular signal transduction | The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. |
| mitochondrion-endoplasmic reticulum membrane tethering | The attachment of a mitochondrion and an endoplasmic reticulum via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles. |
| Notch signaling pathway | The series of molecular signals initiated by an extracellular ligand binding to the receptor Notch on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. |
| protein processing | Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein. |
| regulation of calcium import into the mitochondrion | Any process that modulates the frequency, rate or extent of calcium import into the mitochondrion. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLTFMASDSE | EEVCDERTSL | MSAESPSPRS | CQEGGQGPED | GDSTAQWRIQ | DSEEDGEEDP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DRYVSSGVPG | RPPGPEEELT | LKYGAKHVIM | LSVPVTLCMI | VVVATIKSVR | FYTEKNGQLI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YTPFTEDTPS | VSQRLLNSVL | NTLIMISVIV | VMTIFLVVLY | KYRCYKFIHG | WLIMSSLMLL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FLFTYIYLGE | VLKTYNVAMD | YPTLVLTVWN | FGAVGMVCIH | WKGPLMLQQA | YLIAISALMA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LVFIKYLPEW | SAWVILGAIS | VYDLVAVLCP | KGPLRMLVET | AQERNEPIFP | ALIYSSAMVW |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TVGMAKLDPS | SQGALQLPYD | PEMEEDSYDS | LGEPSYPEVF | EAPLPGYPGE | ELEEEEERGV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KLGLGDFIFY | SVLVGKAAAT | GSGDWNTTLA | CFVAILIGLC | LTLLLLAVFK | KALPALPISI |
| 430 | 440 | ||||
| TFGLVFYFST | DNLVRPFMDT | LAYHQ |