P79204

PR
Gene name
Protein name
Mast cell protease 2
Names
sMCP-2
Species
Ovis aries (Sheep)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

173-242 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P79204

Entry ID Method Resolution Chain Position Source
AF-P79204-F1 Predicted AlphaFoldDB

No variants for P79204

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P79204

No associated diseases with P79204

3 regional properties for P79204

Type Name Position InterPro Accession
domain Serine proteases, trypsin domain 21 - 244 IPR001254
active_site Serine proteases, trypsin family, histidine active site 62 - 67 IPR018114
active_site Serine proteases, trypsin family, serine active site 196 - 207 IPR033116

Functions

Description
EC Number
Subcellular Localization
  • Secreted
  • Cytoplasmic granule
  • Secretory granules
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

1 GO annotations of molecular function

Name Definition
serine-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MHRPPLPLVL LLLCCRAQAG EIIGGTESKP HSRPYMAYLE IVTSQEKQVA CGGFLIRRDF
70 80 90 100 110 120
VLTAAHCAGR SVTVTLGAHN IQKKEDTWQR LEVIKQFPYP KYEPVGVHDI MLLKLKEKAN
130 140 150 160 170 180
LTLAVGTLPL PPHVTFIRPG RMCQVAGWGR TGVKEPASST LQEVKLRLME PRACRHFRAF
190 200 210 220 230 240
DHNLQLCVGN PQSTKSAFKG DSGGPLLCAG VAQGIVSYGL SSAKPPAVFT RISPYRPWID
EVLKEN