P78811

PR
Gene name
fyu1 (SPCC1322.04)
Protein name
Probable UTP--glucose-1-phosphate uridylyltransferase
Names
UDP-glucose pyrophosphorylase, UDPGP, UGPase
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPCC1322.04
EC number
2.7.7.9: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-115 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P78811

Entry ID Method Resolution Chain Position Source
AF-P78811-F1 Predicted AlphaFoldDB

No variants for P78811

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P78811

No associated diseases with P78811

3 regional properties for P78811

Type Name Position InterPro Accession
domain Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic 14 - 299 IPR006075
conserved_site Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site 157 - 171 IPR017958
domain Asn/Gln amidotransferase 341 - 488 IPR018027

Functions

Description
EC Number 2.7.7.9 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
UTP:glucose-1-phosphate uridylyltransferase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose.

2 GO annotations of biological process

Name Definition
glycogen metabolic process The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.
UDP-glucose metabolic process The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDLAPRPLGR QHSKSQSAFA FDNTATSIAA STMKNELNHL ASTVKDPLAK KAFQKEMDNF
70 80 90 100 110 120
FSLFSRYLQE DARGSEINWD LVESPKPEQV VEYDTITEAG GLSRDYLNKL AVLKLNGGLG
130 140 150 160 170 180
TTMGCVGPKS IIEVRDGNSF LDLSVRQIEH LNRKYNVNVP FVLMNSFNTD EATAKVIKKY
190 200 210 220 230 240
EAHKIDILTF NQSRYPRVHK ETLLPVPHTA DSAIDEWYPP GHGDVFEALT NSGIIDTLIA
250 260 270 280 290 300
QGKEYLFVSN IDNLGAVVDL NILNHMVETN AEYLMELTNK TKADVKGGTL IDYDGNVRLL
310 320 330 340 350 360
EIAQVPPQHV EEFKSIKKFK YFNTNNLWFH LPSVKRVVNN HELSMEIIPN KKTIKHKGEN
370 380 390 400 410 420
INIIQLETAA GAAIRHFKNA HGVNVPRRRF LPVKTCSDLL LVKSDLYSIN HGQVEMNPRR
430 440 450 460 470 480
FGGTAPLVKL GAHFKKVADF SAHIPSIPKI LELDHLTITG DVNIGRNVTL KGTVIIVASD
490 500
ANRIDIPNGS VLENCVITGN LNILEH