P78761
Gene name |
qcr2 (SPCC613.10) |
Protein name |
Cytochrome b-c1 complex subunit 2, mitochondrial |
Names |
Complex III subunit 2, Core protein II, Ubiquinol-cytochrome-c reductase complex core protein 2 |
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPCC613.10 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for P78761
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 8Q1B | EM | 340 A | B/M | 1-426 | PDB |
| AF-P78761-F1 | Predicted | AlphaFoldDB |
No variants for P78761
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P78761 | |||||
No associated diseases with P78761
1 regional properties for P78761
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Peptidase M16, N-terminal | 38 - 171 | IPR011765 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrial respiratory chain complex III | A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| structural molecule activity | The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| mitochondrial electron transport, ubiquinol to cytochrome c | The transfer of electrons from ubiquinol to cytochrome c that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex III. |
| proton transmembrane transport | The directed movement of a proton across a membrane. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKSFTRNLRR | FQTPRRNLHG | ISYTPKKVEG | VSFAGRETPT | ATGSLSVVIN | AGSRYQPDAG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VSHLLEKFAF | KTTEERSALR | ITRESELLGG | QLSTQITREH | IILTARFLNE | YLEYYARLLA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EVVDATKFLP | FQLTEEVLPT | ARIESELFRE | DILRVAMAKL | HEKAFHRGIG | NEVYLPASAS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PSISEIKDFA | SKAYVKSNFS | VISSGPDVQK | ASDLCAKYFA | VIPDGSPLKS | APTKISSGES |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RVYSKGTNYF | CLGFPAPAAS | PELFVLSSIL | GGDAAVKWSH | GNTLLAKAAG | TASEYKATAV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ADLTPYSDAS | LLSVVISGSC | PKAIKATASE | SFKALKSLSS | NIPNDVVKSG | IAMAKTKYLS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| AFEPVTLNAI | SASSLVSASK | GSDAFISGFD | KVTPASISKV | VSSLLAKPAS | TVAVGNLDVL |
| PYYDEL |