P78619

PR
Gene name
catB (AN9339)
Protein name
Catalase B
Names
Species
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
KEGG Pathway
ani:AN9339.2
EC number
1.11.1.6: Peroxidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-93 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P78619

Entry ID Method Resolution Chain Position Source
AF-P78619-F1 Predicted AlphaFoldDB

No variants for P78619

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P78619

No associated diseases with P78619

5 regional properties for P78619

Type Name Position InterPro Accession
binding_site Catalase haem-binding site 384 - 392 IPR002226
domain Catalase immune-responsive domain 472 - 535 IPR010582
domain Catalase core domain 54 - 442 IPR011614
active_site Catalase active site 89 - 105 IPR024708
domain Large catalase, C-terminal domain 566 - 719 IPR041399

Functions

Description
EC Number 1.11.1.6 Peroxidases
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

3 GO annotations of molecular function

Name Definition
catalase activity Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
response to oxidative stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRALGLVGLV GVANAVCPYM TGELGRRDTN PDATEATEEF LSEYYLDDTD SYLTTDVGGP
70 80 90 100 110 120
IEDQQSLKAG ARGSTLLEDF IFRQKIQRFD HERVPERAVH ARGAGAHGVF TSYGDFSNIT
130 140 150 160 170 180
AASFLSAEGK ETPVFVRFST VAGSRGSSDL ARDVHGFATR FYTDEGNFDI VGNNIPVFFI
190 200 210 220 230 240
QDAIQFPDLI HAVKPKGDRE IPQAATAHDA AWDFFSQQPS TLHTLLWAMA GHGIPRSFRH
250 260 270 280 290 300
VDGFGVHTFR LVTEDGSTKL VKFHWKTLQG LASMVWEEAQ QISGKNPDYM RQDLFESIEA
310 320 330 340 350 360
GRYPEWELNV QIMDEEDQLR FGFDLFDPTK IVPEEYVPLT PLGKMTLNRN PRNYFAETEQ
370 380 390 400 410 420
VMFQPGHVVR GVDFTEDPLL QQGRLFSYLD TQLNRNGGPN FEQLPINQPR VAIHNNNRDG
430 440 450 460 470 480
AGQMFIPLNP DAYSPNTLKG STLKQANQTA GRGFFTAPDR TANGNLVRAK SSTFDDAWSQ
490 500 510 520 530 540
PRLFWNSLLP AEKQFVVNAI RFENANVKSD VVKNNVIVQL NRISNDLATR VAKAIGVDAP
550 560 570 580 590 600
EPDNTYYHDN TTSNIGAFGH RLQSLAGLKI AVLASVDAEE SFSAATALKA ELSNDNLDVI
610 620 630 640 650 660
VVAERFSNGV NQTYSASDAI QFDAVVVAPG AEKLFGAKSA ANSSSTLYPA GRPLEILVDA
670 680 690 700 710 720
FRFGKPVAAL GSGSTAFDNA GINTAVEGVY VADAVDESFA NNLEEGLTVF KFLDRFALDS
DE