P77671
Gene name |
allB (glxB3, ybbX, b0512, JW0500) |
Protein name |
Allantoinase |
Names |
Allantoin-utilizing enzyme |
Species |
Escherichia coli (strain K12) |
KEGG Pathway |
eco:b0512 |
EC number |
3.5.2.5: In cyclic amides |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for P77671
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 3E74 | X-ray | 210 A | A/B/C/D | 1-453 | PDB |
| AF-P77671-F1 | Predicted | AlphaFoldDB |
No variants for P77671
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P77671 | |||||
No associated diseases with P77671
1 regional properties for P77671
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Amidohydrolase-related | 50 - 431 | IPR006680 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.5.2.5 | In cyclic amides |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| allantoinase activity | Catalysis of the reaction: allantoin + H2O = allantoate. |
| cobalt ion binding | Binding to a cobalt ion (Co). |
| zinc ion binding | Binding to a zinc ion (Zn). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| allantoin assimilation pathway | The pathways by which allantoin is processed and converted to ureidoglycolate, and then into metabolically useful substrates. E. coli are able to utilize allantoin as a sole nitrogen source under anaerobic conditions by converting it to ureidoglycolate; this may be further metabolized to produce glyoxylate and thence 3-phosphoglycerate, or alternatively oxidized to oxolureate, which can converted into oxamate and carbamoylphosphate. This may then be further metabolized to CO2, NH4+ and ATP. |
| purine nucleobase catabolic process | The chemical reactions and pathways resulting in the breakdown of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSFDLIIKNG | TVILENEARV | VDIAVKGGKI | AAIGQDLGDA | KEVMDASGLV | VSPGMVDAHT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HISEPGRSHW | EGYETGTRAA | AKGGITTMIE | MPLNQLPATV | DRASIELKFD | AAKGKLTIDA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AQLGGLVSYN | IDRLHELDEV | GVVGFKCFVA | TCGDRGIDND | FRDVNDWQFF | KGAQKLGELG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QPVLVHCENA | LICDELGEEA | KREGRVTAHD | YVASRPVFTE | VEAIRRVLYL | AKVAGCRLHV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| CHVSSPEGVE | EVTRARQEGQ | DVTCESCPHY | FVLDTDQFEE | IGTLAKCSPP | IRDLENQKGM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| WEKLFNGEID | CLVSDHSPCP | PEMKAGNIMK | AWGGIAGLQS | CMDVMFDEAV | QKRGMSLPMF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GKLMATNAAD | IFGLQQKGRI | APGKDADFVF | IQPNSSYVLT | NDDLEYRHKV | SPYVGRTIGA |
| 430 | 440 | 450 | |||
| RITKTILRGD | VIYDIEQGFP | VAPKGQFILK | HQQ |