Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P77622

Entry ID Method Resolution Chain Position Source
AF-P77622-F1 Predicted AlphaFoldDB

No variants for P77622

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P77622

No associated diseases with P77622

4 regional properties for P77622

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 8 - 243 IPR003439
domain AAA+ ATPase domain 41 - 220 IPR003593
domain Oligopeptide/dipeptide ABC transporter, C-terminal 220 - 305 IPR013563
conserved_site ABC transporter-like, conserved site 143 - 157 IPR017871

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing A complex for the transport of metabolites into the cell, consisting of 5 subunits: two ATP-binding subunits, two membrane spanning subunits, and one substrate-binding subunit. In organisms with two membranes, the substrate-binding protein moves freely in the periplasmic space and joins the other subunits only when bound with substrate. In organisms with only one membrane the substrate-binding protein is tethered to the cytoplasmic membrane and associated with the other subunits. Transport of the substrate across the membrane is driven by the hydrolysis of ATP.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

1 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

2 GO annotations of biological process

Name Definition
dipeptide transport The directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSDTLLTLRD VHINFPARKN WLGKTTEHVH AINGIDLQIR RGETLGIVGE SGCGKSTLAQ
70 80 90 100 110 120
LLMGMLQPSH GQYIRSGSQR IMQMVFQDPL SSLNPRLPVW RIITEPLWIA KRSSEQQRRA
130 140 150 160 170 180
LAEELAVQVG IRPEYLDRLP HAFSGGQRQR IAIARALSSQ PDVIVLDEPT SALDISVQAQ
190 200 210 220 230 240
ILNLLVTLQE NHGLTYVLIS HNVSVIRHMS DRVAVMYLGQ IVELGDAQQV LTAPAHPYTR
250 260 270 280 290 300
LLLDSLPAID KPLEEEWALR KTDLPGNRTL PQGCFFYERC PLATHGCEVR QSLAIREDGR
ELRCWRAL