P77434

PR
Gene name
alaC
Protein name
Glutamate-pyruvate aminotransferase AlaC
Names
Species
Escherichia coli (strain K12)
KEGG Pathway
eco:b2379
EC number
2.6.1.2: Transaminases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-105 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P77434

Entry ID Method Resolution Chain Position Source
AF-P77434-F1 Predicted AlphaFoldDB

No variants for P77434

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P77434

No associated diseases with P77434

1 regional properties for P77434

Type Name Position InterPro Accession
domain Aminotransferase, class I/classII 37 - 376 IPR004839

Functions

Description
EC Number 2.6.1.2 Transaminases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
L-alanine:2-oxoglutarate aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + L-alanine = L-glutamate + pyruvate.
pyridoxal phosphate binding Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
transaminase activity Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid.

3 GO annotations of biological process

Name Definition
alanine biosynthetic process The chemical reactions and pathways resulting in the formation of alanine, 2-aminopropanoic acid.
D-alanine biosynthetic process The chemical reactions and pathways resulting in the formation of D-alanine, the D-enantiomer of the amino acid alanine, i.e (2R)-2-aminopropanoic acid.
L-alanine biosynthetic process from pyruvate The chemical reactions and pathways resulting in the formation of alanine from other compounds, including pyruvate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MADTRPERRF TRIDRLPPYV FNITAELKMA ARRRGEDIID FSMGNPDGAT PPHIVEKLCT
70 80 90 100 110 120
VAQRPDTHGY STSRGIPRLR RAISRWYQDR YDVEIDPESE AIVTIGSKEG LAHLMLATLD
130 140 150 160 170 180
HGDTVLVPNP SYPIHIYGAV IAGAQVRSVP LVEGVDFFNE LERAIRESYP KPKMMILGFP
190 200 210 220 230 240
SNPTAQCVEL EFFEKVVALA KRYDVLVVHD LAYADIVYDG WKAPSIMQVP GARDVAVEFF
250 260 270 280 290 300
TLSKSYNMAG WRIGFMVGNK TLVSALARIK SYHDYGTFTP LQVAAIAALE GDQQCVRDIA
310 320 330 340 350 360
EQYKRRRDVL VKGLHEAGWM VEMPKASMYV WAKIPEPYAA MGSLEFAKKL LNEAKVCVSP
370 380 390 400 410
GIGFGDYGDT HVRFALIENR DRIRQAIRGI KAMFRADGLL PASSKHIHEN AE