Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P76168

Entry ID Method Resolution Chain Position Source
AF-P76168-F1 Predicted AlphaFoldDB

No variants for P76168

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P76168

No associated diseases with P76168

3 regional properties for P76168

Type Name Position InterPro Accession
domain Integrase, catalytic domain 167 - 378 IPR002104
domain Min27-like integrase, DNA-binding domain 11 - 39 IPR022000
domain Core-binding (CB) domain 51 - 146 IPR044068

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

5 GO annotations of biological process

Name Definition
DNA integration The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
DNA recombination Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
establishment of integrated proviral latency A process by which the virus integrates into the host genome and establishes as a stable provirus or prophage.
viral entry into host cell The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.
viral genome integration into host DNA The insertion into a host genome of viral DNA, usually by the action of an integrase enzyme. Once integrated, the provirus persists in the host cell and serves as a template for the transcription of viral genes and replication of the viral genome, leading to the production of new viruses.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MITDVWKYRG KSTGELRSSV CYAIKTGVFD YAKQFPSSRN LEKFGEARQD LTIKELAEKF
70 80 90 100 110 120
LALKETEVAK TSLNTYRAVI KNILSIIGEK NLASSINKEK LLEVRKELLT GYQIPKSNYI
130 140 150 160 170 180
VTQPGRSAVT VNNYMTNLNA VFQFGVDNGY LADNPFKGIS PLKESRTIPD PLSREEFIRL
190 200 210 220 230 240
IDACRNQQAK NLWCVSVYTG VRPGELCALG WEDIDLKNGT MMIRRNLAKD RFTVPKTQAG
250 260 270 280 290 300
TNRVIHLIKP AIDALRSQMT LTRLSKEHII DVHFREYGRT EKQKCTFVFQ PEVSARVKNY
310 320 330 340 350 360
GDHFTVDSIR QMWDAAIKRA GLRHRKSYQS RHTYACWSLT AGANPAFIAN QMGHADAQMV
370 380 390
FQVYGKWMSE NNNAQVALLN TQLSEFAPTM PHNEAMKN