P75906

PR
Gene name
pgaB (ycdR, b1023, JW5142)
Protein name
Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase
Names
PGA N-deacetylase, Poly-beta-1,6-GlcNAc N-deacetylase
Species
Escherichia coli (strain K12)
KEGG Pathway
eco:b1023
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-74 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

9 structures for P75906

Entry ID Method Resolution Chain Position Source
3VUS X-ray 165 A A/B 42-309 PDB
4F9D X-ray 190 A A/B 42-655 PDB
4F9J X-ray 210 A A/B 42-655 PDB
4P7L X-ray 180 A A 310-672 PDB
4P7N X-ray 189 A A 310-672 PDB
4P7O X-ray 148 A A/B 310-672 PDB
4P7Q X-ray 165 A A 310-672 PDB
4P7R X-ray 180 A A 310-672 PDB
AF-P75906-F1 Predicted AlphaFoldDB

No variants for P75906

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P75906

No associated diseases with P75906

2 regional properties for P75906

Type Name Position InterPro Accession
domain NodB homology domain 102 - 349 IPR002509
domain Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, C-terminal 318 - 645 IPR032772

Functions

Description
EC Number
Subcellular Localization
  • Cell outer membrane ; Lipid-anchor ; Periplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cell outer membrane A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.

2 GO annotations of molecular function

Name Definition
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds.
hydrolase activity, hydrolyzing O-glycosyl compounds Catalysis of the hydrolysis of any O-glycosyl bond.

4 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
cell adhesion involved in biofilm formation The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm.
macromolecule deacylation The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a macromolecule.
single-species biofilm formation A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLRNGNKYLL MLVSIIMLTA CISQSRTSFI PPQDRESLLA EQPWPHNGFV AISWHNVEDE
70 80 90 100 110 120
AADQRFMSVR TSALREQFAW LRENGYQPVS IAQIREAHRG GKPLPEKAVV LTFDDGYQSF
130 140 150 160 170 180
YTRVFPILQA FQWPAVWAPV GSWVDTPADK QVKFGDELVD REYFATWQQV REVARSRLVE
190 200 210 220 230 240
LASHTWNSHY GIQANATGSL LPVYVNRAYF TDHARYETAA EYRERIRLDA VKMTEYLRTK
250 260 270 280 290 300
VEVNPHVFVW PYGEANGIAI EELKKLGYDM FFTLESGLAN ASQLDSIPRV LIANNPSLKE
310 320 330 340 350 360
FAQQIITVQE KSPQRIMHID LDYVYDENLQ QMDRNIDVLI QRVKDMQIST VYLQAFADPD
370 380 390 400 410 420
GDGLVKEVWF PNRLLPMKAD IFSRVAWQLR TRSGVNIYAW MPVLSWDLDP TLTRVKYLPT
430 440 450 460 470 480
GEKKAQIHPE QYHRLSPFDD RVRAQVGMLY EDLAGHAAFD GILFHDDALL SDYEDASAPA
490 500 510 520 530 540
ITAYQQAGFS GSLSEIRQNP EQFKQWARFK SRALTDFTLE LSARVKAIRG PHIKTARNIF
550 560 570 580 590 600
ALPVIQPESE AWFAQNYADF LKSYDWTAIM AMPYLEGVAE KSADQWLIQL TNQIKNIPQA
610 620 630 640 650 660
KDKSILELQA QNWQKNGQHQ AISSQQLAHW MSLLQLNGVK NYGYYPDNFL HNQPEIDLIR
670
PEFSTAWYPK ND