P75867

PR
Gene name
ycbZ (b0955, JW0938)
Protein name
Putative Lon protease homolog
Names
ATP-dependent protease La homolog
Species
Escherichia coli (strain K12)
KEGG Pathway
eco:b0955
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

357-427 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P75867

Entry ID Method Resolution Chain Position Source
AF-P75867-F1 Predicted AlphaFoldDB

No variants for P75867

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P75867

No associated diseases with P75867

2 regional properties for P75867

Type Name Position InterPro Accession
domain Peptidase S16, Lon proteolytic domain 346 - 543 IPR008269
domain Lon protease, AAA domain 140 - 225 IPR041699

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP-dependent peptidase activity Catalysis of the hydrolysis of peptide bonds, driven by ATP hydrolysis.
serine-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

2 GO annotations of biological process

Name Definition
protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTITKLAWRD LVPDTDSYQE IFAQPHLIDE NDPLFSDTQP RLQFALEQLL HTRASSSFML
70 80 90 100 110 120
AKAPEESEYL NLIANAARTL QSDAGQLVGG HYEVSGHSIR LRHAVSADDN FATLTQVVAA
130 140 150 160 170 180
DWVEAEQLFG CLRQFNGDIT LQPGLVHQAN GGILIISLRT LLAQPLLWMR LKNIVNRERF
190 200 210 220 230 240
DWVAFDESRP LPVSVPSMPL KLKVILVGER ESLADFQEME PELSEQAIYS EFEDTLQIVD
250 260 270 280 290 300
AESVTQWCRW VTFTARHNHL PAPGADAWPI LIREAARYTG EQETLPLSPQ WILRQCKEVA
310 320 330 340 350 360
SLCDGDTFSG EQLNLMLQQR EWREGFLAER MQDEILQEQI LIETEGERIG QINALSVIEF
370 380 390 400 410 420
PGHPRAFGEP SRISCVVHIG DGEFTDIERK AELGGNIHAK GMMIMQAFLM SELQLEQQIP
430 440 450 460 470 480
FSASLTFEQS YSEVDGDSAS MAELCALISA LADVPVNQSI AITGSVDQFG RAQPVGGLNE
490 500 510 520 530 540
KIEGFFAICQ QRELTGKQGV IIPTANVRHL SLHSELVKAV EEGKFTIWAV DDVTDALPLL
550 560 570 580
LNLVWDGEGQ TTLMQTIQER IAQASQQEGR HRFPWPLRWL NWFIPN