P75590
Gene name |
infB (MPN_155, MP676) |
Protein name |
Translation initiation factor IF-2 |
Names |
|
Species |
Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) (Mycoplasmoides pneumoniae) |
KEGG Pathway |
mpn:MPN_155 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P75590
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P75590-F1 | Predicted | AlphaFoldDB |
No variants for P75590
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P75590 | |||||
No associated diseases with P75590
5 regional properties for P75590
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Translational (tr)-type GTP-binding domain | 119 - 288 | IPR000795 |
| domain | Translation elongation factor EFTu-like, domain 2 | 538 - 605 | IPR004161 |
| domain | Small GTP-binding protein domain | 124 - 278 | IPR005225 |
| domain | Translation initiation factor IF- 2, domain 3 | 393 - 507 | IPR023115 |
| domain | Translation initiation factor IF-2, domain II | 297 - 390 | IPR044145 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| translation initiation factor activity | Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSKHKPRHFQ | KNKFDNRAKT | SAKQQFRQVK | TGVKDGVFVY | KGPLTVSEFC | LKTNIPTANI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IKHFFLNGVP | LTLNSVLSTE | QLADACVNFG | FDFKVETEIT | HDNIISNIKF | DDDPTQLSPR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PPIVTIMGHV | DHGKTSLLDA | IRQTNTAAKE | FGGITQKIGA | YQVKNQEGKT | ITFIDTPGHE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AFTGMRARGA | QVTDIVVLVV | AGDDGLKQQT | EEAISHAKSA | KTPIIVFINK | MDKPTANPDM |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VIQQLNKFDL | VPEEWGGDTI | FVKGSALTKE | GIQELLDSIL | LVAEVEDYKA | NFNAHSSGYA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IEVQTTKGLG | PTATIIVKRG | TLKIGDIVVL | GPAWGKVRTM | QDENGVHLQE | AMPSKPVQIS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GFDIVPVAGE | KFIVFDDEKD | AKLIANKFRE | QQKQKLNTTQ | INEELKQKIK | SKEIKVLNLI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| FKVDSDGSLA | AIKQAMQSID | VPGMSVNIIH | SGVGLISEND | IMLAKASGAL | LFSLNLGLSQ |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VVKNIASLQG | VKVDVHYHIP | KLAEEIENIL | KGQLEPVYED | VELGRAEVLQ | LWYHSKVGHI |
| 550 | 560 | 570 | 580 | 590 | 600 |
| AGTLVKTGKV | KRGALCKLLR | RNETIYEGRV | DSLKSEKNPV | NQMEAGKNCG | IVINGCEDIQ |
| 610 | |||||
| VCDIILVYEK | QEVKSKS |