Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

31 structures for P75577

Entry ID Method Resolution Chain Position Source
7OOD EM 340 A a 1-287 PDB
7P6Z EM 350 A a 1-287 PDB
7PAH EM 950 A a 1-287 PDB
7PAI EM 670 A a 1-287 PDB
7PAJ EM 730 A a 1-287 PDB
7PAK EM 530 A a 1-287 PDB
7PAL EM 470 A a 1-287 PDB
7PAM EM 680 A a 1-287 PDB
7PAN EM 970 A a 1-287 PDB
7PAO EM 700 A a 1-287 PDB
7PAQ EM 890 A a 1-287 PDB
7PAR EM 820 A a 1-287 PDB
7PAS EM 1600 A a 1-287 PDB
7PAT EM 920 A a 1-287 PDB
7PAU EM 830 A a 1-287 PDB
7PH9 EM 870 A a 1-287 PDB
7PHA EM 850 A a 1-287 PDB
7PHB EM 490 A a 1-287 PDB
7PHC EM 990 A a 1-287 PDB
7PI8 EM 890 A a 1-287 PDB
7PI9 EM 630 A a 1-287 PDB
7PIA EM 1360 A a 1-287 PDB
7PIB EM 470 A a 1-287 PDB
7PIC EM 910 A a 1-287 PDB
7PIO EM 950 A a 1-287 PDB
7PIP EM 930 A a 1-287 PDB
7PIQ EM 970 A a 1-287 PDB
7PIR EM 1210 A a 1-287 PDB
7PIS EM 1500 A a 1-287 PDB
7PIT EM 570 A a 1-287 PDB
AF-P75577-F1 Predicted AlphaFoldDB

No variants for P75577

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P75577

No associated diseases with P75577

3 regional properties for P75577

Type Name Position InterPro Accession
domain Ribosomal Proteins L2, RNA binding domain 46 - 122 IPR022666
domain Ribosomal protein L2, C-terminal 130 - 261 IPR022669
conserved_site Ribosomal protein L2, conserved site 226 - 237 IPR022671

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
large ribosomal subunit The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site).

3 GO annotations of molecular function

Name Definition
rRNA binding Binding to a ribosomal RNA.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.
transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.

1 GO annotations of biological process

Name Definition
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPIKKIISRS NSGIHHSTVI DYKKLLTTNK NKPEKSLLVT LKKHGGRNNQ GKITVRHQGG
70 80 90 100 110 120
RNKRKYRIID FKRTHYDNIE ATVKSIEYDP NRSCFVSLIT YANGAKSYII SPDGIKVGDK
130 140 150 160 170 180
ILASEHPIDI KPGFSMPLAF IPEGTQVHNI ELHPKGGGQI ARSAGSYARI LGQDETGKYV
190 200 210 220 230 240
ILQLLSGETR KFLKECRATV GVVSNLDHNL VVIGKAGRNR HRGIRPTVRG SAMNPNDHPH
250 260 270 280
GGGEGRSPVG RDAPRTPWGK RHMGVKTRNM KKASTNLIIR NRKGEQY