P75544

PR
Gene name
fusA (fus, MPN_227, MP604)
Protein name
Elongation factor G
Names
EF-G
Species
Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) (Mycoplasmoides pneumoniae)
KEGG Pathway
mpn:MPN_227
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

250-324 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

7 structures for P75544

Entry ID Method Resolution Chain Position Source
7PAO EM 700 A 9 1-688 PDB
7PAQ EM 890 A 9 1-688 PDB
7PAR EM 820 A 9 1-688 PDB
7PIB EM 470 A 9 1-688 PDB
7PIS EM 1500 A 9 1-688 PDB
7PIT EM 570 A 9 1-688 PDB
AF-P75544-F1 Predicted AlphaFoldDB

No variants for P75544

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P75544

No associated diseases with P75544

9 regional properties for P75544

Type Name Position InterPro Accession
domain Elongation factor EFG, domain V-like 596 - 683 IPR000640
domain Translational (tr)-type GTP-binding domain 8 - 282 IPR000795
domain Translation elongation factor EFTu-like, domain 2 321 - 387 IPR004161
domain Small GTP-binding protein domain 12 - 180 IPR005225
domain Translation elongation factor EFG/EF2, domain IV 476 - 594 IPR005517
domain Elongation factor G, domain III 403 - 477 IPR009022
conserved_site Tr-type G domain, conserved site 51 - 66 IPR031157
domain EFG, domain V 599 - 676 IPR035649
domain Elongation Factor G, domain II 401 - 474 IPR041095

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation elongation factor activity Functions in chain elongation during polypeptide synthesis at the ribosome.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MARTVDLINF RNFGIMAHID AGKTTTSERI LFHSGRIHKI GETHDGESVM DWMEQEKERG
70 80 90 100 110 120
ITITSAATSV SWKNCSLNLI DTPGHVDFTV EVERSLRVLD GAIAVLDAQM GVEPQTETVW
130 140 150 160 170 180
RQASRYEVPR IIFVNKMDKT GANFERSVQS IQQRLGVKAV PIQLPIGAEN DFNGIIDLIE
190 200 210 220 230 240
EKVYFFDGGK EEKAEEKPIP DQFKDQVKQM RAHLVEEVAN FDDQLMADYL EGKEISIADI
250 260 270 280 290 300
KRCIRKGVIG CQFFPVLCGS AFKNKGIKLL LDAVVDFLPS PVDVPQAKAY GEDGNEVLIS
310 320 330 340 350 360
ASDDAPFVGL AFKVATDPFV GRLTFVRVYS GVLKSGSYVK NVRKNKKERV SRLVKMHAQN
370 380 390 400 410 420
RNEIEEIRAG DICAIIGLKD TTTGETLVDD KIDVQLEAMQ FAQPVISLAV EPKTKADQEK
430 440 450 460 470 480
MSIALSKLAE EDPTFKTFTD PETGQTIIAG MGELHLDILV DRMRREFKVE VNVGAPQVSF
490 500 510 520 530 540
RETFNKESEV EGKYIKQSGG RGQYGHVKIR FEPNKDKGFE FVDKIVGGRI PREYIKPVQA
550 560 570 580 590 600
GLENAMASGP LAGYPMIDIK ATLFDGSFHE VDSSEMAFKI AASLALKEAG KVCSPVLLEP
610 620 630 640 650 660
IMAIEVTVPE QYFGDTMGDI SSRRGLIEGT EQRDNVQVIK AKVPLKEMFG YATDLRSFSQ
670 680
GRGNYVMQFS HYAETPKSVV NEIIATKK