P75478

PR
Gene name
scpA (MPN_300, MP536)
Protein name
Segregation and condensation protein A
Names
Species
Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) (Mycoplasmoides pneumoniae)
KEGG Pathway
mpn:MPN_300
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

392-506 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P75478

Entry ID Method Resolution Chain Position Source
AF-P75478-F1 Predicted AlphaFoldDB

No variants for P75478

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P75478

No associated diseases with P75478

1 regional properties for P75478

Type Name Position InterPro Accession
domain Dihydrofolate reductase domain 1 - 166 IPR001796

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
dihydrofolate reductase activity Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+.

4 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
chromosome segregation The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
tetrahydrofolate biosynthetic process The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MITLIWCQDK HFGIGRDNTI PWKLTEANQH FYNTTKNQTV VMGYNTFQEL GDKLTDHNVV
70 80 90 100 110 120
VLSKKHFEEL QNNTNIKVFN SIEKLLQHHF NRDLYVIGGK QIFHHFIELA DRLIISVLPV
130 140 150 160 170 180
DFKCNLRLKL GLDSFELMQE QQHSQFKVQY WHKKHPERLS FNVFLEDYNG TLPNLLELLI
190 200 210 220 230 240
DKKFNLHQVD IAKITTQYLH LINTNLNKQA IEPITDYLVI TSRIVEQKAN NLLQINDIAL
250 260 270 280 290 300
DSDFLDNKLR DKLVAQLVEY KRYRESLDDF EKLRINRLAY FSKDNDFNRF IQTVDKSNTE
310 320 330 340 350 360
PVKIEDELPN YVSVLKLHHA MNKLMQRWRA QFLANKNISI QELSIEQVQA EILATIKQFG
370 380 390 400 410 420
YHSVSLKRVL LKVNHHISLM YFITAFVALL VLINNQIIDI EQTSFDDELY ICLLDSSRIE
430 440 450 460 470 480
QLQETPEAMV ERAVKQRQEA QELARQVARE KAIANAQKRE AYLKAKYGKD YLTREQFLKL
490 500
SPEERAAHVA KMKQLKLVKN DNGRDN