P75433

PR
Gene name
MPN_345 (H91_orf206, MP491)
Protein name
Putative type I restriction enzyme MpnIIP endonuclease subunit C-terminal part
Names
R protein C-terminal part, Putative type-1 restriction enzyme MpnORFDP R protein part 3, MpnORFDBP
Species
Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) (Mycoplasmoides pneumoniae)
KEGG Pathway
mpn:MPN_345
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

101-172 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P75433

Entry ID Method Resolution Chain Position Source
AF-P75433-F1 Predicted AlphaFoldDB

No variants for P75433

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P75433

No associated diseases with P75433

2 regional properties for P75433

Type Name Position InterPro Accession
domain Helicase superfamily 1/2, ATP-binding domain 42 - 205 IPR014001
domain SWI2/SNF2 ATPase 49 - 205 IPR040980

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
type I site-specific deoxyribonuclease activity Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions, driven by ATP hydrolysis. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA.

1 GO annotations of biological process

Name Definition
DNA restriction-modification system A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRWSDSENNK IDYIEDFATH FLNKNALLNV ICKFCVFRSN SDLWVMRPYQ ICATERILEK
70 80 90 100 110 120
IKEDNRNSKN SKNASKGGCI WHSTGSGKTL TSFKAVQLAS EIDFVDKVLF VVDRKDLDNQ
130 140 150 160 170 180
TIEEYEKFQA GSVSETENTN DLKEKILDDS TATRAIVTTI HKLKRLIDQR SKLKDEDLKK
190 200
KNIVLIFDEC HRSQFGKMKQ EIDEFF