P75172

PR
Gene name
MPN_623 (C12_orf450, MP219)
Protein name
Probable ATP-dependent RNA helicase MG425 homolog
Names
Species
Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) (Mycoplasmoides pneumoniae)
KEGG Pathway
mpn:MPN_623
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

351-450 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P75172

Entry ID Method Resolution Chain Position Source
AF-P75172-F1 Predicted AlphaFoldDB

No variants for P75172

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P75172

No associated diseases with P75172

4 regional properties for P75172

Type Name Position InterPro Accession
domain Helicase, C-terminal 234 - 384 IPR001650
domain DEAD/DEAH box helicase domain 27 - 193 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 22 - 226 IPR014001
domain RNA helicase, DEAD-box type, Q motif 3 - 31 IPR014014

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDSTFNELGV SPALIATLKD NNINQPTTIQ QLAIPQFLQH QNLIVHSPTG TGKTAVFGIP
70 80 90 100 110 120
VIETLLKKPS KGTTQTLVVA PTRELAEQIK TTFINFAKHT HLKVVSLIGG IPIWQQLKQL
130 140 150 160 170 180
ENQPEIVVGT MGRVMDLLER GVIKFEHLEH LIIDEVDLML DRGFKRKLFD LLSRIEKFEQ
190 200 210 220 230 240
IAVYSASYNE ETIETAKQIT KNGIFLAAPE LKQNAPEPDN KLIDQFVCYL FSNRKKQALY
250 260 270 280 290 300
SLVSQTRAKS IIVFCDTKKL VDELCIFLRK NDVKTYPLHG DKAQFIRERN LKLFANTTAP
310 320 330 340 350 360
IVLVTTDLIG RGIHVEGVDM VVNYSACVNF ETYLHRMGRT GRNNHKGSCI TFCTSHEKQA
370 380 390 400 410 420
FLKLLEQVND KRISPLRPMR LRLIPLKCKT QPKKGKLSLQ SVQKIYVNPR SNGTFKRVPL
430 440
AGDLFKSRMR QPERDMQKNK LHDSDWQSNM