Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P74511

Entry ID Method Resolution Chain Position Source
AF-P74511-F1 Predicted AlphaFoldDB

No variants for P74511

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P74511

1 associated diseases with P74511

[MIM: 614678]: Pontocerebellar hypoplasia 1B (PCH1B)

A severe autosomal recessive neurologic disorder characterized by a combination of cerebellar and spinal motor neuron degeneration beginning at birth. There is diffuse muscle weakness, progressive microcephaly, global developmental delay, and brainstem involvement. {ECO:0000269|PubMed:22544365}. Note=The disease is caused by variants affecting the gene represented in this entry.

Without disease ID
  • A severe autosomal recessive neurologic disorder characterized by a combination of cerebellar and spinal motor neuron degeneration beginning at birth. There is diffuse muscle weakness, progressive microcephaly, global developmental delay, and brainstem involvement. {ECO:0000269|PubMed:22544365}. Note=The disease is caused by variants affecting the gene represented in this entry.

No regional properties for P74511

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P74511

Functions

Description
EC Number
Subcellular Localization
  • Cellular thylakoid membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane-derived thylakoid membrane The pigmented membrane of a plasma membrane-derived thylakoid.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTSYSSATAR AEMSELRRLK SLLPPELQSW VMVEGSTEVN PPLIRSEELG RDEIEIQVDL
70 80 90 100 110 120
AKWENLAIDQ RNLLFWHEVA RIQSDTIPRE GWEMAALAIG LGGAVGELWV QDGLLLLLAL
130 140 150 160 170 180
GLCGISGYRL WQKNNGEKRI KEAIEADEKA ITLATRFGYT LPNAYKSLGS AFKTLIEQTP
190 200 210
NRRQRKQYET RLQALRQSAA KMKAKTQKAK AL