Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P74422

Entry ID Method Resolution Chain Position Source
AF-P74422-F1 Predicted AlphaFoldDB

No variants for P74422

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P74422

No associated diseases with P74422

2 regional properties for P74422

Type Name Position InterPro Accession
domain Transcription regulator HTH, LysR 1 - 61 IPR000847
domain LysR, substrate-binding 86 - 300 IPR005119

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.

1 GO annotations of biological process

Name Definition
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRLEQLQAFL KVAELGSFQQ AALQSEVTQS TISRQIQGLE SALKCQLFHR GAQAKLTVAG
70 80 90 100 110 120
ELFLRRARKI CQEWDVASEE ISSLFQGKQT ELCVAAIHSV CVSSLPSLLP KFCLGHPQIQ
130 140 150 160 170 180
LRVTALGSDR ALKVLQDGLV DVAIIMSHRN LTNTKELAIK PLYEEQICIL MASDHPLTTK
190 200 210 220 230 240
KFITWENLGP YPQVIFKDGY RMRRLVEDEF SRREIPLNVS LELNIPEAFY GVVQGSEMIA
250 260 270 280 290 300
LMPQSLVTPV IDNPNFSVRY LFCPESGDRQ DFRRQVSVVT TVDRLQIPPV AEFFNLVVDH
YRCGALTVK