P74180

PR
Gene name
ftsW (slr1267)
Protein name
Probable peptidoglycan glycosyltransferase FtsW
Names
PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase
Species
Synechocystis sp (strain PCC 6803 / Kazusa)
KEGG Pathway
syn:slr1267
EC number
2.4.1.129: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

333-393 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P74180

Entry ID Method Resolution Chain Position Source
AF-P74180-F1 Predicted AlphaFoldDB

No variants for P74180

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P74180

No associated diseases with P74180

1 regional properties for P74180

Type Name Position InterPro Accession
conserved_site Cell cycle, FtsW / RodA / SpoVE, conserved site 335 - 359 IPR018365

Functions

Description
EC Number 2.4.1.129 Hexosyltransferases
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
  • Localizes to the division septum
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cell division site The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
lipid-linked peptidoglycan transporter activity Enables the directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells.
peptidoglycan glycosyltransferase activity Catalysis of the reaction: [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-diphosphoundecaprenol + GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-diphosphoundecaprenol + undecaprenyl diphosphate.

5 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
cell wall organization A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
peptidoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.
regulation of cell shape Any process that modulates the surface configuration of a cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MITAANLLRI IFPFYDPEVL RWSGEARLMR TLFFAWMAMG VVVLFSASYA ESLDTSGTGL
70 80 90 100 110 120
SIILKQIAYL WLGLNIFNFL VRLPLQVCLK LVPWFLIVVL LLIFLTKSGL GVEVNGARRW
130 140 150 160 170 180
ISLGPILIQP SEFMKPCLVL QAANLFGNWH RFPWRSRLIW LGIFALTLGS ILLQPNLSTT
190 200 210 220 230 240
ALCGMGLWLI ALASGLPWIY LISTALLGIT TAVTSISIRD YQRARVTSFL DPFADPRGDG
250 260 270 280 290 300
YQLVQSLYAI ASGGVLGRGF GMSQQKLFYL PIQTTDFIFA VFAEEFGLVG CITFLAFLGL
310 320 330 340 350 360
FTTMGLRVAM RCRHRVKRLI GLGVVIFLVG QSLLNIGVAS GALPTTGLPL PFFSYGGSSC
370 380 390
LSSLVLAGLL VRVARESNEA EVIPLGTKTA PAV