Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P74070

Entry ID Method Resolution Chain Position Source
AF-P74070-F1 Predicted AlphaFoldDB

No variants for P74070

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P74070

No associated diseases with P74070

3 regional properties for P74070

Type Name Position InterPro Accession
domain Translation elongation factor EFTs/EF1B, dimerisation 71 - 275 IPR014039
conserved_site Translation elongation factor Ts, conserved site 12 - 27 IPR018101-1
conserved_site Translation elongation factor Ts, conserved site 75 - 85 IPR018101-2

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
translation elongation factor activity Functions in chain elongation during polypeptide synthesis at the ribosome.

1 GO annotations of biological process

Name Definition
translational elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAEITAQLVK ELREKTGAGM MDCKKALKEN EGDLEKSIEW LRQKGIASAD KKSGRTAAEG
70 80 90 100 110 120
LVHSYIHFGG RIGVLVEVNC ETDFVARGDR FKDLVNDVAM QIAACPNVEY VSVADIPQEM
130 140 150 160 170 180
VAKEKEIEMG RDDLGKKPAN IKEKIVQGRI DKRLKELSLL DQPYIKDQNL TIEELVKQAI
190 200 210
AELGENIQVR RFIRFNLGEG IEKAETNFAE EVAAAAKG