P74007
Gene name |
spoT (slr1325) |
Protein name |
Probable guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase |
Names |
Penta-phosphate guanosine-3'-pyrophosphohydrolase, (ppGpp)ase |
Species |
Synechocystis sp (strain PCC 6803 / Kazusa) |
KEGG Pathway |
syn:slr1325 |
EC number |
3.1.7.2: Diphosphoric monoester hydrolases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P74007
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P74007-F1 | Predicted | AlphaFoldDB |
No variants for P74007
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P74007 | |||||
No associated diseases with P74007
4 regional properties for P74007
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Orn/DAP/Arg decarboxylase 2, N-terminal | 107 - 371 | IPR022644 |
| binding_site | Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site | 116 - 134 | IPR022653 |
| domain | Arginine decarboxylase, helical bundle domain | 395 - 476 | IPR040634 |
| domain | Arginine decarboxylase, C-terminal helical | 605 - 658 | IPR041128 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.7.2 | Diphosphoric monoester hydrolases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity | Catalysis of the reaction: guanosine 3',5'-bis(diphosphate) + H2O = guanosine 5'-diphosphate + diphosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| guanosine tetraphosphate biosynthetic process | The chemical reactions and pathways resulting in the formation of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNAVAALPTP | TIHTTCAQDI | HDIELPQWLE | DCLQQWQREI | EQGQDETTAP | HCLICRAFCF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AYDLHAQQRR | KSGEPYIAHP | VAVAGLLRDL | GGDEAMIAAG | FLHDVVEDTD | ISIEQIEALF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GEETASLVEG | VTKLSKFNFS | STTEHQAENF | RRMFLAMAKD | IRVIVVKLAD | RLHNMRTLDA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LSPEKQRRIA | RETKDIFAPL | ANRLGIWRFK | WELEDLSFKY | LEPDSYRKIQ | SLVVEKRGDR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ESRLETVKDM | LRFRLRDEGI | EHFELQGRPK | HLYGIYYKMT | SQDKAFEEIY | DIAALRIIVE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SKGECYRALS | VVHDVFKPIP | GRFKDYIGLP | KPNRYQSLHT | TVLGLTSRPL | EIQIRTEEMH |
| 370 | 380 | 390 | 400 | 410 | 420 |
| HVAEYGIAAH | WKYKESGGSE | NATLTSTDEK | FTWLRQLLDW | QSDLKDAQEY | VENLKQNLFD |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DDVYVFTPKG | EVISLARGAT | PVDFAYRIHT | EVGHHMKGAR | VNGQWLGVDT | RLKNGDIVEI |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VTQKNSHPSL | DWLNFVVTPS | ARHRIRQWFK | RSRRDENILR | GRELLEKELG | KTGLEALLKS |
| 550 | 560 | 570 | 580 | 590 | 600 |
| EPMQKTAERC | NYQNVEDLLA | GLGYGEITSN | SVVNRLRENN | VNNVKNSQSS | QEVTLASSPQ |
| 610 | 620 | 630 | 640 | 650 | 660 |
| VHPPTPPATG | KDNSPIAGIE | GLLYHIAGCC | HPLPGEPIMG | VVTRGARGIS | IHRQGCHNLE |
| 670 | 680 | 690 | 700 | 710 | 720 |
| QMDGDRLIPV | RWNPNTNNHQ | TYPVDIVIEA | IDRVGVLKDI | LSRLSDNHIN | VRNADVKTHL |
| 730 | 740 | 750 | |||
| GRPAIISLKI | DIHDYQQLLG | IMAKIKNMSD | VMDLRRVISG |