P73863
Gene name |
nhaS1 (slr1727) |
Protein name |
Low-affinity Na(+)/H(+) antiporter NhaS1 |
Names |
Sodium/proton antiporter NhaS1 |
Species |
Synechocystis sp (strain PCC 6803 / Kazusa) |
KEGG Pathway |
syn:slr1727 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P73863
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P73863-F1 | Predicted | AlphaFoldDB |
No variants for P73863
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P73863 | |||||
No associated diseases with P73863
1 regional properties for P73863
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Cation/H+ exchanger | 21 - 405 | IPR006153 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| potassium:proton antiporter activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in). |
| sodium:proton antiporter activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| potassium ion transmembrane transport | A process in which a potassium ion is transported from one side of a membrane to the other. |
| regulation of intracellular pH | Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion. |
| sodium ion import across plasma membrane | The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDTAVNESLS | ISYNLEQFLI | VLSVSLSIAT | LSKTVPILRK | IPYTLLLVIV | GMALAFVDVK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LINLSPELIM | EIFLPPLLFE | AAWNLQWRNL | KENWFPITLF | ATLGVVICVV | GIAFPLSYWG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GMELAIAFLA | AAALSATDPV | SVIALFKELG | ASKKLNTLME | GESLFNDGVA | VVVFLILVGI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PLGTSTFDLS | VTLARFVTVI | GIGVGCGLVI | GFSLSLLTQR | FDLPFVEQSL | TLVSAYGAYI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LAENLGGSGV | IGVVVVGMVL | GNYGSRIGMN | PRTRLIVSIF | WEFVAFFVNS | IIFLLIGDQI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GLSSLSDHLN | LILIAIAAVV | VTRLVSVFGL | SLISNKVSDQ | ISSTHITLQE | QTVLWWGGLR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GSVAIAVALS | VPQAIAERQA | IIDIVFGVVL | FTLLVQGLTT | QFVLKGLDLI | GDQPQRLEYA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ELVSRQIALR | RVLAELEKTD | EFPDINPERL | RYKQELVQGQ | LQSVTDKLKL | LLQEYPLLQE |
| 490 | 500 | 510 | 520 | ||
| VANKKFDQTV | LDIEAETYAD | LIRMGRLEEN | IMPLLVTLEG | ENVAEPS |