P72854

PR
Gene name
sir (slr0963)
Protein name
Sulfite reductase [ferredoxin]
Names
Species
Synechocystis sp (strain PCC 6803 / Kazusa)
KEGG Pathway
syn:slr0963
EC number
1.8.7.1: With an iron-sulfur protein as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-55 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P72854

Entry ID Method Resolution Chain Position Source
AF-P72854-F1 Predicted AlphaFoldDB

No variants for P72854

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P72854

No associated diseases with P72854

6 regional properties for P72854

Type Name Position InterPro Accession
domain Nitrite/Sulfite reductase ferredoxin-like domain 92 - 152 IPR005117-1
domain Nitrite/Sulfite reductase ferredoxin-like domain 338 - 400 IPR005117-2
binding_site Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site 412 - 430 IPR006066-1
binding_site Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site 461 - 479 IPR006066-2
domain Nitrite/sulphite reductase 4Fe-4S domain 162 - 313 IPR006067-1
domain Nitrite/sulphite reductase 4Fe-4S domain 412 - 549 IPR006067-2

Functions

Description
EC Number 1.8.7.1 With an iron-sulfur protein as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
sulfite reductase complex (NADPH) A multisubunit iron flavoprotein, which in yeast is composed of 2 alpha and 2 beta subunits. Catalyzes the reduction of sulfite to sulfide.

5 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.
sulfite reductase (ferredoxin) activity Catalysis of the reaction: hydrogen sulfide + 3 oxidized ferredoxin + 3 H2O = sulfite + 3 reduced ferredoxin.
sulfite reductase activity Catalysis of the reaction: hydrogen sulfide + acceptor + 3 H2O = sulfite + reduced acceptor.

1 GO annotations of biological process

Name Definition
sulfate assimilation The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVTTPTAAPR KPSKVEGIKE RSNYLREPLA TELLNDANYF TDDAVQILKF HGSYQQDNRD
70 80 90 100 110 120
NRVKGQEKDY QFMLRTRNPG GLIPAQLYTA LDDLSKTHGN QTLRVTTRQG LQIHGIVKKD
130 140 150 160 170 180
LKMAIATVVN NLGSTLGACG DINRNVMAPA APFRDKPEYG YAWDYANKVA DLLSPQSGAY
190 200 210 220 230 240
YEIWLDGEKV ISGEEAPEVK AARQKDLNGT NLNDPKEPIY GQQFMPRKFK ISVTVPGDNS
250 260 270 280 290 300
IDVYTHDISL VVITDRHGEL RGFNVLAGGG LGRTHNKEET FARAADPIGY VSKDDVYDLV
310 320 330 340 350 360
KAIVATQRDY GDRHNRRHAR MKYLLADWGV EKFRKQVETY MGKPFQSFKP LPAWRYQDYL
370 380 390 400 410 420
GWHEQGDGKL FFGLSVENGR IKDEGDFQLK TALRKVVDQF QLPLRLTANH NILLYDINAQ
430 440 450 460 470 480
DKAAIEQIFQ QHGVVTDPEA IDTLVRYSMA CPALPTCGLA VTESERIMPS VNARLRDLLN
490 500 510 520 530 540
SLDLPNESIV TRMTGCPNGC ARPYMAEIGF VGSAPNSYQV WLGGSPNQER LAAAYTEKMP
550 560 570 580 590 600
LEQLESLFEP LFVYFKQSRK GKESFGDFCH RVGFTALREF SHGYTAPAKG GKNRKNQRRV
610 620 630
SLSDEMYAQL KARSERDNCP MNQIVQQALT AYLGK