P71040
Gene name |
clsA (ywnE, BSU36590) |
Protein name |
Major cardiolipin synthase ClsA |
Names |
CL synthase 2 |
Species |
Bacillus subtilis (strain 168) |
KEGG Pathway |
bsu:BSU36590 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P71040
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P71040-F1 | Predicted | AlphaFoldDB |
No variants for P71040
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P71040 | |||||
No associated diseases with P71040
6 regional properties for P71040
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ABC transporter type 1, transmembrane domain MetI-like | 1 - 66 | IPR000515 |
| domain | Phospholipase D/Transphosphatidylase | 217 - 244 | IPR001736-1 |
| domain | Phospholipase D/Transphosphatidylase | 395 - 422 | IPR001736-2 |
| domain | Phospholipase D-like domain | 135 - 277 | IPR025202-1 |
| domain | Phospholipase D-like domain | 323 - 449 | IPR025202-2 |
| domain | Cardiolipin synthase N-terminal | 13 - 55 | IPR027379 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| cardiolipin synthase activity | Catalysis of the reaction: phosphatidylglycerol + phosphatidylglycerol = diphosphatidylglycerol (cardiolipin) + glycerol. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| cardiolipin biosynthetic process | The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol. |
| sporulation | The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction. |
| transmembrane transport | The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSISSILLSL | FFILNILLAI | IVIFKERRDA | SASWAWLLVL | FFIPVLGFIL | YLLFGHNLRR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KHLFQWEDRK | KIGIERLLKH | QLEDLETKQF | QFNNRATFDN | KDLIYMLIMN | NHAVFTEDNS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VDVITDGRDK | FQRLLSDISK | AKDHIHLQYY | IYKGDELGKK | LRDALIQKAK | EGVQVRVLYD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ELGSRTLRKK | FFKELREAGG | HVEVFFPSKL | RPINLRLNYR | NHRKLVIIDG | MTGYVGGFNV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GDEYLGLNPK | FGYWRDTHIR | LQGTAVHAIQ | TRFILDWNQA | SHHHTLTYIP | NHFPDYGPKG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NVGMQIVTSG | PDSEWEQIKN | GYIKMISNAK | RSILIQTPYF | IPDASLLDAL | RIACLSGIDV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NIMIPNKPDH | AFVYWATLSY | IGDLLKAGAT | VYIYDNGFIH | AKTIVVDDEI | ASVGTANIDV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| RSFRLNFEVN | AFIYDITIAK | KLVSTFKEDL | LVSRKFTYEE | YLQRPLWIRI | KESVSRLLSP |
| IL |