P70352

PR
Gene name
Art5
Protein name
Ecto-ADP-ribosyltransferase 5
Names
ADP-ribosyltransferase C2 and C3 toxin-like 5, ARTC5, Mono(ADP-ribosyl)transferase 5, NAD(P)(+)--arginine ADP-ribosyltransferase 5, YAC-2
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:11875
EC number
2.4.2.31: Pentosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

134-213 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P70352

Entry ID Method Resolution Chain Position Source
AF-P70352-F1 Predicted AlphaFoldDB

22 variants for P70352

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3388936512 21 V>I No EVA
rs224579265 22 R>Q No EVA
rs217708641 24 V>I No EVA
rs3388932878 47 M>I No EVA
rs3388929261 62 H>L No EVA
rs264920739 81 H>P No EVA
rs3388932897 91 A>G No EVA
rs254769039 92 Q>P No EVA
rs3388918683 144 L>M No EVA
rs3388913855 200 F>L No EVA
rs3388888965 207 F>L No EVA
rs239826403 210 P>S No EVA
rs3388909469 222 E>D No EVA
rs3388933101 226 P>S No EVA
rs3388929046 228 H>Y No EVA
rs3388936522 243 S>I No EVA
rs31841534 248 W>S No EVA
rs31840698 268 R>H No EVA
rs254755709 274 R>K No EVA
rs31840695 277 G>R No EVA
rs3388918717 281 A>T No EVA
rs3388933107 310 P>C No EVA

No associated diseases with P70352

No regional properties for P70352

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P70352

Functions

Description
EC Number 2.4.2.31 Pentosyltransferases
Subcellular Localization
  • Secreted
  • Membrane
  • Membrane-associated
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
anchored component of membrane The component of a membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

2 GO annotations of molecular function

Name Definition
NAD+ ADP-ribosyltransferase activity Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.
NAD+-protein-arginine ADP-ribosyltransferase activity Catalysis of the reaction: L-arginyl- + NAD+ = H+ + (ADP-D-ribosyl)-L-arginyl-

1 GO annotations of biological process

Name Definition
peptidyl-arginine ADP-ribosylation The transfer, from NAD, of ADP-ribose to peptidyl-arginine to form omega-N-(ADP-ribosyl)-L-arginine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MILEDLLMVL SCLSLHALWK VRAVPILPLS LVPDTFDDAY VGCSEEMEEK AGLLLKEEMA
70 80 90 100 110 120
RHALLRESWE AAQEAWAHRR HKLTLPPGFK AQHGVAIMVY TNSSNTLYWE LNQAVRTGGG
130 140 150 160 170 180
SRELYMRHFP FKALHFYLTR ALQLLRGSGG CSRGPGEVVF RGVGSLHFEP KRLGDSVRLG
190 200 210 220 230 240
QFTSSSVDER VARRFGNATF FNLRTCFGAP IQALSVFPEE REVLIPPHEV FLVTGFSQDG
250 260 270 280 290 300
AQSIVTLWSY DQTCSHFNCA YLGGEKRRGC VSSRAVGQPE APSTEALALQ SGKTLLLDPR
KLQLSRAGP