Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P69073
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P69073-F1 | Predicted | AlphaFoldDB |
No variants for P69073
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P69073 | |||||
No associated diseases with P69073
6 regional properties for P69073
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| active_site | Cysteine peptidase, cysteine active site | 148 - 159 | IPR000169 |
| domain | Peptidase C2, calpain, catalytic domain | 81 - 405 | IPR001300 |
| domain | EF-hand domain | 658 - 693 | IPR002048 |
| domain | Peptidase C2, calpain, large subunit, domain III | 419 - 550 | IPR022682 |
| domain | Peptidase C2, calpain, domain III | 412 - 558 | IPR022683 |
| domain | Calpain subdomain III | 411 - 560 | IPR033883 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleosome | A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| protein heterodimerization activity | Binding to a nonidentical protein to form a heterodimer. |
| structural constituent of chromatin | The action of a molecule that contributes to the structural integrity of chromatin. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MARTKQTARK | STGGKAPRKQ | LATKAARKSA | PATGGVKKPH | RYRPGTVALR | EIRRYQKSTE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LLIRKLPFQR | LVREIAQDFK | TELRFQSSAV | MALQEASEAY | LVGLFEDTNL | CAIHAKRVTI |
| 130 | |||||
| MPKDIQLARR | IRGERA |