P68790

PR
Gene name
fusA (fus)
Protein name
Elongation factor G
Names
EF-G, 85 kDa vitronectin-binding protein
Species
Staphylococcus aureus
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

381-536 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

5 structures for P68790

Entry ID Method Resolution Chain Position Source
2XEX X-ray 190 A A/B 1-693 PDB
3ZZ0 X-ray 280 A A/B 1-693 PDB
3ZZT X-ray 295 A A/B 1-693 PDB
3ZZU X-ray 298 A A/B 1-693 PDB
AF-P68790-F1 Predicted AlphaFoldDB

No variants for P68790

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P68790

No associated diseases with P68790

9 regional properties for P68790

Type Name Position InterPro Accession
domain Elongation factor EFG, domain V-like 599 - 686 IPR000640
domain Translational (tr)-type GTP-binding domain 8 - 282 IPR000795
domain Translation elongation factor EFTu-like, domain 2 323 - 390 IPR004161
domain Small GTP-binding protein domain 9 - 180 IPR005225
domain Translation elongation factor EFG/EF2, domain IV 478 - 597 IPR005517
domain Elongation factor G, domain III 404 - 479 IPR009022
conserved_site Tr-type G domain, conserved site 51 - 66 IPR031157
domain EFG, domain V 602 - 679 IPR035649
domain Elongation Factor G, domain II 403 - 476 IPR041095

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation elongation factor activity Functions in chain elongation during polypeptide synthesis at the ribosome.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAREFSLEKT RNIGIMAHID AGKTTTTERI LYYTGRIHKI GETHEGASQM DWMEQEQDRG
70 80 90 100 110 120
ITITSAATTA AWEGHRVNII DTPGHVDFTV EVERSLRVLD GAVTVLDAQS GVEPQTETVW
130 140 150 160 170 180
RQATTYGVPR IVFVNKMDKL GANFEYSVST LHDRLQANAA PIQLPIGAED EFEAIIDLVE
190 200 210 220 230 240
MKCFKYTNDL GTEIEEIEIP EDHLDRAEEA RASLIEAVAE TSDELMEKYL GDEEISVSEL
250 260 270 280 290 300
KEAIRQATTN VEFYPVLCGT AFKNKGVQLM LDAVIDYLPS PLDVKPIIGH RASNPEEEVI
310 320 330 340 350 360
AKADDSAEFA ALAFKVMTDP YVGKLTFFRV YSGTMTSGSY VKNSTKGKRE RVGRLLQMHA
370 380 390 400 410 420
NSRQEIDTVY SGDIAAAVGL KDTGTGDTLC GEKNDIILES MEFPEPVIHL SVEPKSKADQ
430 440 450 460 470 480
DKMTQALVKL QEEDPTFHAH TDEETGQVII GGMGELHLDI LVDRMKKEFN VECNVGAPMV
490 500 510 520 530 540
SYRETFKSSA QVQGKFSRQS GGRGQYGDVH IEFTPNETGA GFEFENAIVG GVVPREYIPS
550 560 570 580 590 600
VEAGLKDAME NGVLAGYPLI DVKAKLYDGS YHDVDSSEMA FKIAASLALK EAAKKCDPVI
610 620 630 640 650 660
LEPMMKVTIE MPEEYMGDIM GDVTSRRGRV DGMEPRGNAQ VVNAYVPLSE MFGYATSLRS
670 680 690
NTQGRGTYTM YFDHYAEVPK SIAEDIIKKN KGE