P67863

PR
Gene name
Protein name
Snake venom vascular endothelial growth factor toxin vammin
Names
svVEGF, VEGF-F
Species
Vipera ammodytes ammodytes (Western sand viper)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

79-145 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for P67863

Entry ID Method Resolution Chain Position Source
1WQ8 X-ray 190 A A 26-134 PDB
AF-P67863-F1 Predicted AlphaFoldDB

No variants for P67863

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P67863

No associated diseases with P67863

2 regional properties for P67863

Type Name Position InterPro Accession
conserved_site Ribosome-inactivating protein conserved site 196 - 212 IPR017988
domain Protein of unknown function DUF6598 371 - 552 IPR046533

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

2 GO annotations of molecular function

Name Definition
growth factor activity The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
toxin activity Interacting selectively with one or more biological molecules in another (target) organism, initiating pathogenesis (leading to an abnormal, generally detrimental state) in the target organism. The activity should refer to an evolved function of the active gene product, i.e. one that was selected for. Examples include the activity of botulinum toxin, and snake venom.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAAYLLAVAI LFCIQGWPSG TVQGQVRPFL EVHERSACQA RETLVPILQE YPDEISDIFR
70 80 90 100 110 120
PSCVAVLRCS GCCTDESLKC TPVGKHTVDL QIMRVNPRTQ SSKMEVMKFT EHTACECRPR
130 140
RKQGEPDGPK EKPRRGGVRA RFPFV