P65868

PR
Gene name
pth
Protein name
Peptidyl-tRNA hydrolase
Names
PTH
Species
Staphylococcus aureus (strain N315)
KEGG Pathway
sau:SA0460
EC number
3.1.1.29: Carboxylic ester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

68-144 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P65868

Entry ID Method Resolution Chain Position Source
AF-P65868-F1 Predicted AlphaFoldDB

No variants for P65868

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P65868

No associated diseases with P65868

6 regional properties for P65868

Type Name Position InterPro Accession
repeat HAT (Half-A-TPR) repeat 87 - 119 IPR003107-1
repeat HAT (Half-A-TPR) repeat 121 - 153 IPR003107-2
repeat HAT (Half-A-TPR) repeat 156 - 188 IPR003107-3
repeat HAT (Half-A-TPR) repeat 305 - 336 IPR003107-4
repeat HAT (Half-A-TPR) repeat 489 - 521 IPR003107-5
repeat HAT (Half-A-TPR) repeat 525 - 558 IPR003107-6

Functions

Description
EC Number 3.1.1.29 Carboxylic ester hydrolases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
aminoacyl-tRNA hydrolase activity Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.

1 GO annotations of biological process

Name Definition
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKCIVGLGNI GKRFELTRHN IGFEVVDYIL EKNNFSLDKQ KFKGAYTIER MNGDKVLFIE
70 80 90 100 110 120
PMTMMNLSGE AVAPIMDYYN VNPEDLIVLY DDLDLEQGQV RLRQKGSAGG HNGMKSIIKM
130 140 150 160 170 180
LGTDQFKRIR IGVGRPTNGM TVPDYVLQRF SNDEMVTMEK VIEHAARAIE KFVETSRFDH
VMNEFNGEVK