P65731
Gene name |
pknI (BQ2027_MB2938C) |
Protein name |
Serine/threonine-protein kinase PknI |
Names |
|
Species |
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) |
KEGG Pathway |
|
EC number |
2.7.11.1: Protein-serine/threonine kinases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P65731
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P65731-F1 | Predicted | AlphaFoldDB |
No variants for P65731
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P65731 | |||||
No associated diseases with P65731
1 regional properties for P65731
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Protein kinase domain | 12 - 252 | IPR000719 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.11.1 | Protein-serine/threonine kinases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| protein serine kinase activity | Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate. |
| protein serine/threonine kinase activity | Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein phosphorylation | The process of introducing a phosphate group on to a protein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MALASGVTFA | GYTVVRMLGC | SAMGEVYLVQ | HPGFPGWQAL | KVLSPAMAAD | DEFRRRFQRE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TEVAARLFHP | HILEVHDRGE | FDGQLWIAMD | YVDGIDATQH | MADRFPAVLP | VGEVLAIVTA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VAGALDYAHQ | RGLLHRDVNP | ANVVLTSQSA | GDQRILLADF | GIASQPSYPA | PELSAGADVD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GRADQYALAL | TAIHLFAGAP | PVDRSHTGPL | QPPKLSAFRP | DLARLDGVLS | RALATAPADR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FGSCREFADA | MNEQAGVAIA | DQSSGGVDAS | EVTAAAGEEA | YVVDYPAYGW | PEAVDCKEPS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ARAPAPAAPT | PQRRGSMLQS | AAGVLARRLD | NFSTATKAPA | SPTRRRPRRI | LVGAVAVLLL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| AGLFAVGIVI | GRKTNTTATE | VARPPTSGSA | VPSAPTTTVA | VTAPVPLDGT | YRIEIQRSKQ |
| 430 | 440 | 450 | 460 | 470 | 480 |
| TYDYTPTPQP | PDVNTWWAFR | TSCTPTECLA | AATMLDDNDH | TQAKTPPVRP | FLMQFGEGQW |
| 490 | 500 | 510 | 520 | 530 | 540 |
| KSRPETVQFP | CVGPNGSPST | QATTQLLALR | PQPQGDLVGE | MVVTVHSNEC | GQQGAVIRIP |
| 550 | 560 | 570 | 580 | ||
| AVASRSGDLP | PAVTVPDPAT | IPDTPDTTST | ATLTPPTTTA | PGPGR |