P65554

PR
Gene name
rppH
Protein name
RNA pyrophosphohydrolase
Names
(Di)nucleoside polyphosphate hydrolase
Species
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
KEGG Pathway
stm:STM3004
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

126-176 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P65554

Entry ID Method Resolution Chain Position Source
AF-P65554-F1 Predicted AlphaFoldDB

No variants for P65554

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P65554

No associated diseases with P65554

4 regional properties for P65554

Type Name Position InterPro Accession
domain NUDIX hydrolase domain 6 - 149 IPR000086
conserved_site NUDIX hydrolase, conserved site 38 - 59 IPR020084
domain NUDIX hydrolase 33 - 47 IPR020476-1
domain NUDIX hydrolase 47 - 62 IPR020476-2

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
mRNA 5'-diphosphatase activity Catalysis of the removal of a 5' terminal diphosphate from the 5'-triphosphate end of an mRNA, leaving a 5'-monophosphate end.

1 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIDDDGYRPN VGIVICNRQG QVMWARRFGQ HSWQFPQGGI NPGESAEQAM YRELFEEVGL
70 80 90 100 110 120
SRKDVRILAS TRNWLRYKLP KRLVRWDTKP VCIGQKQKWF LLQLMSADAE INMQTSSTPE
130 140 150 160 170
FDGWRWVSYW YPVRQVVSFK RDVYRRVMKE FASVVMALQD NPPKLQSAPA YRRKRG