P65466
Gene name |
murB |
Protein name |
UDP-N-acetylenolpyruvoylglucosamine reductase |
Names |
UDP-N-acetylmuramate dehydrogenase |
Species |
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) |
KEGG Pathway |
spn:SP_1390 |
EC number |
1.3.1.98: With NAD(+) or NADP(+) as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P65466
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P65466-F1 | Predicted | AlphaFoldDB |
No variants for P65466
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P65466 | |||||
No associated diseases with P65466
Functions
| Description | ||
|---|---|---|
| EC Number | 1.3.1.98 | With NAD(+) or NADP(+) as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| FAD binding | Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. |
| UDP-N-acetylmuramate dehydrogenase activity | Catalysis of the reaction: UDP-N-acetylmuramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADPH + H+. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| cell cycle | The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. |
| cell division | The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. |
| cell wall organization | A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. |
| peptidoglycan biosynthetic process | The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls. |
| regulation of cell shape | Any process that modulates the surface configuration of a cell. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSVREKMLEI | LEGIDIRFKE | PLHSYSYTKV | GGEADYLVFP | RNRFELARVV | KFANQENIPW |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MVLGNASNII | VRDGGIRGFV | ILCDKLNNVS | VDGYTIEAEA | GANLIETTRI | ALRHSLTGFE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FACGIPGSVG | GAVFMNAGAY | GGEIAHILQS | CKVLTKDGEI | ETLSAKDLAF | GYRHSAIQES |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GAVVLSVKFA | LAPGTHQVIK | QEMDRLTHLR | ELKQPLEYPS | CGSVFKRPVG | HFAGQLISEA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GLKGYRIGGV | EVSEKHAGFM | INVADGTAKD | YEDLIQSVIE | KVKEHSGITL | EREVRILGES |
| 310 | |||||
| LSVAKMYAGG | FTPCKR |